Deubiquitylating enzymes and DNA damage response pathways
X Jacq, M Kemp, NMB Martin, SP Jackson - Cell biochemistry and …, 2013 - Springer
Covalent post-translational modification of proteins by ubiquitin and ubiquitin-like factors has
emerged as a general mechanism to regulate myriad intra-cellular processes. The addition …
emerged as a general mechanism to regulate myriad intra-cellular processes. The addition …
Plant-derived natural compounds as an emerging antiviral in combating COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a human virus that burst
at Wuhan in China and spread quickly over the world, leading to millions of deaths globally …
at Wuhan in China and spread quickly over the world, leading to millions of deaths globally …
Therapeutic prospects of naturally occurring p38 MAPK inhibitors tanshinone IIA and pinocembrin for the treatment of SARS‐CoV‐2‐induced CNS complications
M Valipour - Phytotherapy Research, 2023 - Wiley Online Library
P38 mitogen‐activated protein kinase (p38 MAPK) signaling pathway is closely related to
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) replication and …
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) replication and …
Protease targeted COVID-19 drug discovery: What we have learned from the past SARS-CoV inhibitors?
The fascinating similarity between the SARS-CoV and SARS-CoV-2, inspires scientific
community to investigate deeper into the SARS-CoV proteases such as main protease …
community to investigate deeper into the SARS-CoV proteases such as main protease …
[HTML][HTML] Natural and semi-synthetic flavonoid anti-SARS-CoV-2 agents for the treatment of long COVID-19 disease and neurodegenerative disorders of cognitive …
The aim of this review is to highlight the beneficial attributes of flavonoids, a diverse family of
widely-distributed polyphenolic phytochemicals that have beneficial cell and tissue …
widely-distributed polyphenolic phytochemicals that have beneficial cell and tissue …
Coronaviruses and nature's pharmacy for the relief of coronavirus disease 2019
KC Chinsembu - Revista Brasileira de Farmacognosia, 2020 - Springer
Current challenges to the treatment of coronavirus disease 2019 should open new
prospects in the search for novel drugs from medicinal plants and other natural products …
prospects in the search for novel drugs from medicinal plants and other natural products …
[HTML][HTML] Safe, high-throughput screening of natural compounds of MERS-CoV entry inhibitors using a pseudovirus expressing MERS-CoV spike protein
Middle East respiratory syndrome coronavirus (MERS-CoV) belongs to the Coronaviridae
family of enveloped, positive-sense, single-stranded RNA viruses [1]. MERS-CoV is mainly …
family of enveloped, positive-sense, single-stranded RNA viruses [1]. MERS-CoV is mainly …
Computational determination of potential multiprotein targeting natural compounds for rational drug design against SARS-COV-2
SARS-CoV-2 caused the current COVID-19 pandemic and there is an urgent need to
explore effective therapeutics that can inhibit enzymes that are imperative in virus …
explore effective therapeutics that can inhibit enzymes that are imperative in virus …
Papain-like proteases as coronaviral drug targets: Current inhibitors, opportunities, and limitations
AI Petushkova, AA Zamyatnin Jr - Pharmaceuticals, 2020 - mdpi.com
Papain-like proteases (PLpro) of coronaviruses (CoVs) support viral reproduction and
suppress the immune response of the host, which makes CoV PLpro perspective …
suppress the immune response of the host, which makes CoV PLpro perspective …
An Attention towards the Prophylactic and Therapeutic Options of Phytochemicals for SARS-CoV-2: A Molecular Insight
The novel pathogenic virus was discovered in Wuhan, China (December 2019), and quickly
spread throughout the world. Further analysis revealed that the pathogenic strain of virus …
spread throughout the world. Further analysis revealed that the pathogenic strain of virus …