Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

Over the past century, evidence has emerged that endocrine disrupting chemicals (EDCs)
have an impact on reproductive health. An increased frequency of reproductive disorders …

Phthalates are commonly used as plasticizers in the manufacturing of flexible polyvinyl
chloride products. Large production volumes of phthalates and their widespread use in …

BACKGROUND Chemotherapy treatment in premenopausal women is associated with an
increased risk of premature ovarian failure (POF) but the exact mechanism through which …

Primordial follicle assembly in the mouse occurs during perinatal ages and largely
determines the ovarian reserve that will be available to support the reproductive life span …

BACKGROUND The first small follicles to appear in the mammalian ovaries are primordial
follicles. The initial pool of primordial follicles serves as the source of developing follicles …

Numerous evidences have alerted on the toxic effects of the exposure to glyphosate on
living organisms. Glyphosate is the herbicide most used in crops such as maize and …

Zearalenone (ZEA), one of the most prevalent estrogenic mycotoxins, is mainly produced by
Fusarium fungi and has been proven to affect the reproductive capacity of animals …

The adult mammalian ovary is devoid of definitive germline stem cells. As such, female
reproductive senescence largely results from the depletion of a finite ovarian follicle pool …

Widespread use of the endocrine disrupting chemical bisphenol A (BPA) in consumer
products has resulted in nearly continuous human exposure. In rodents, low-dose …