Abstract Hypothesis Amorphous Magnesium-Calcium Phosphate (AMCP) particles in the
distal small intestine have been shown to have a fundamental role in mammals' immune …

Nanoparticle-structuring aimed at the acetic acid (A) transporter on intestinal epithelial cells
and tumor cells is a new potential strategy to enhance oral bioavailability and anti-tumor …

Proteolysis-targeting chimeras (PROTACs) have emerged as potentially effective
therapeutic medicines, but their high molecular weight and poor solubility directly impact …

Full understanding of the barrier property of mucosal tissues is imperative for development
of successful mucosal drug delivery strategies, particularly for biologics and nanomedicines …

Background and aims Functional dyspepsia (FD) is a common gastrointestinal disorder
associated with brain–gut interaction disturbances. In recent years, accumulating evidence …

A preclinical porcine model that reliably predicts human food effect of fenofibrate was
developed. Fenofibrate was administered to pigs as model compound with a positive food …

Pharmacomagnetography involves the simultaneous assessment of solid dosage forms
(SDFs) in the human gastrointestinal (GI) tract and the drug plasmatic concentration, using a …

The needles of conifer trees are one of the richest sources of natural polyprenols. Polyprenol
homologs from Abies sibirica L. lipophilic 80% purified extract were analyzed and quantified …

ABSTRACT Introduction: Three-dimensional (3D) cell cultures have become increasingly
important materials to investigate biological processes and drug efficacy and toxicity. The …

Background and aims Bariatric surgery remains a mainstay for treatment of morbid obesity.
However, long-term adverse outcomes include chronic abdominal pain and persistent …