Immunomodulatory application of engineered hydrogels in regenerative medicine

W Wei, Q Zhang, W Zhou, Z Liu, Y Wang… - Applied Materials …, 2019 - Elsevier
With unique physicochemical properties such as high-water content, drug loading capacity,
biodegradability, and biocompatibility, hydrogels are promising materials for biomedical …

[HTML][HTML] Glomerular endothelial cells are the coordinator in the development of diabetic nephropathy

T Li, K Shen, J Li, SWS Leung, T Zhu, Y Shi - Frontiers in Medicine, 2021 - frontiersin.org
The prevalence of diabetes is consistently rising worldwide. Diabetic nephropathy is a
leading cause of chronic renal failure. The present study aimed to explore the crosstalk …

[HTML][HTML] Relationship between macrophages and tissue microenvironments in Diabetic kidneys

J Yan, X Li, N Liu, JC He, Y Zhong - Biomedicines, 2023 - mdpi.com
Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease. Increasing
evidence has suggested that inflammation is a key microenvironment involved in the …

Prevalence of nephropathy in patients with type 2 diabetes in Iran: a systematic review and meta-analysis based on geographic information system (GIS)

E Rabieenia, R Jalali, M Mohammadi - Diabetes & Metabolic Syndrome …, 2020 - Elsevier
Background and aims Diabetic nephropathy are one of the most important causes of renal
failure and dysfunction in diabetic patients and imposes high costs for the healthcare …

[HTML][HTML] Association of glomerular complement C4c deposition with the progression of diabetic kidney disease in patients with type 2 diabetes

S Duan, L Sun, G Nie, J Chen, C Zhang, H Zhu… - Frontiers in …, 2020 - frontiersin.org
Objectives: As accumulating data supporting the potential role of the complement system in
the pathogenesis of diabetic kidney disease (DKD), the present study aimed to explore the …

Cellular crosstalk of glomerular endothelial cells and podocytes in diabetic kidney disease

S Jiang, M Luo, X Bai, P Nie, Y Zhu, H Cai, B Li… - Journal of Cell …, 2022 - Springer
Diabetic kidney disease (DKD) is a serious microvascular complication of diabetes and is
the leading cause of end-stage renal disease (ESRD). Persistent proteinuria is an important …

[HTML][HTML] Immune-related SERPINA3 as a biomarker involved in diabetic nephropathy renal tubular injury

Z Fan, Y Gao, N Jiang, F Zhang, S Liu, Q Li - Frontiers in Immunology, 2022 - frontiersin.org
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease and has become
a serious medical issue globally. Although it is known to be associated with glomerular …

Quality of evidence supporting the role of tripterygium glycosides for the treatment of diabetic kidney disease: an overview of systematic reviews and meta-analyses

H Shi, P Deng, C Dong, R Lu, G Si… - Drug Design …, 2023 - Taylor & Francis
Background Tripterygium glycosides (TG) is widely used in the treatment of diabetic kidney
disease (DKD) in China. To systematically assess and synthesize the available evidence …

[HTML][HTML] Novel biomarkers and therapeutic approaches for diabetic retinopathy and nephropathy: Recent progress and future perspectives

Z Xie, X Xiao - Frontiers in Endocrinology, 2022 - frontiersin.org
The global burden due to microvascular complications in patients with diabetes mellitus
persists and even increases alarmingly, the intervention and management are now …

Nonproteinuric progressive diabetic kidney disease

C Zoccali, F Mallamaci - Current opinion in nephrology and …, 2019 - journals.lww.com
Studies focusing on risk factors for DKD in nonproteinuric patients are a clinical research
priority. The CKD273 classifier is a promising biomarker for the early identification of …