A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …

Influenza A viruses (IAVs) are contagious pathogens responsible for severe respiratory
infection in humans and animals worldwide. Upon detection of IAV infection, host immune …

Emerging and re-emerging respiratory viral infections pose a tremendous threat to human
society, as exemplified by the ongoing COVID-19 pandemic. Upon viral invasion of the …

Tissue-resident memory T cells (TRM) patrol nonlymphoid organs and provide superior
protection against pathogens that commonly infect mucosal and barrier tissues, such as the …

Laboratory mice comprise an expeditious model for preclinical vaccine testing; however,
vaccine immunogenicity in these models often inadequately translates to humans …

Impaired vaccine responses in older individuals are associated with alterations in both the
quantity and quality of the T-cell compartment with age. As reviewed herein, the T-cell …

The influenza virus-host interaction is a classic arms race. The recurrent and evolving nature
of the influenza virus family allows a single host to be infected several times. Locked in co …

Influenza viruses are highly transmissible, both within and between host species. The
severity of the disease they cause is highly variable, from the mild and inapparent through to …

Background Prophylactic strategies are urgently needed for prevention of severe
inflammatory responses to respiratory viral infections. Bacterial-host interactions may modify …

Epidemiological studies suggest that India has the largest number of dengue virus infection
cases worldwide. However, there is minimal information about the immunological responses …