Pre-eclampsia remains a leading cause of maternal and perinatal mortality and morbidity. It
is a pregnancy-specific disease characterised by de-novo development of concurrent …

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by
the immune system of its mother, thus critically contributing to fetal–maternal tolerance. The …

Transcription, translation and subsequent protein modification represent the transfer of
genetic information from the archival copy of DNA to the short-lived messenger RNA, usually …

In this review, the authors summarize current knowledge on maternal nutritional
requirements during pregnancy, with a focus on the nutrients that have been most commonly …

Preeclampsia is a multiorgan, heterogeneous disorder of pregnancy associated with
significant maternal and neonatal morbidity and mortality. Optimal strategies in the care of …

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Cellular commitment to a specific lineage is controlled by differential silencing of genes,
which in turn depends on epigenetic processes such as DNA methylation and histone …

Rationale: Prenatal exposure to tobacco smoke increases the risk for diseases later in the
child's life that may be mediated through alterations in DNA methylation. Objectives: To …

Epigenetic mechanisms, which control chromatin structure and function, mediate changes in
gene expression that occur in response to diverse stimuli. Recent research has established …

The epigenomes of higher organisms constantly change over time. Many of these epigenetic
changes are necessary to direct normal cellular development and differentiation in the …