[HTML][HTML] Triple versus LAMA/LABA combination therapy for patients with COPD: a systematic review and meta-analysis

A Koarai, M Yamada, T Ichikawa, N Fujino… - Respiratory …, 2021 - Springer
Background Recently, the addition of inhaled corticosteroid (ICS) to long-acting muscarinic
antagonist (LAMA) and long-acting beta-agonist (LABA) combination therapy has been …

[HTML][HTML] LABA/LAMA as first-line therapy for COPD: a summary of the evidence and guideline recommendations

M Miravitlles, T Kawayama, M Dreher - Journal of Clinical Medicine, 2022 - mdpi.com
Inhaled bronchodilators (alone or in combination) are the cornerstone of treatment for
symptomatic patients with COPD, either as initial/first-line treatment or for second …

COPD‐X Australian guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2022 update

E Dabscheck, J George, K Hermann… - Medical Journal of …, 2022 - Wiley Online Library
Introduction Chronic obstructive pulmonary disease (COPD) is a treatable and preventable
disease characterised by persistent respiratory symptoms and chronic airflow limitation on …

[HTML][HTML] Reducing the risk of mortality in chronic obstructive pulmonary disease with pharmacotherapy: a narrative review

M Mintz, I Barjaktarevic, DA Mahler, B Make… - Mayo Clinic …, 2023 - Elsevier
In 2020, chronic obstructive pulmonary disease (COPD) was the fifth leading cause of death
in the United States excluding COVID-19, and its mortality burden has been rising since the …

Benefit/risk profile of single-inhaler triple therapy in COPD

J Bourbeau, M Bafadhel, NC Barnes… - … Journal of Chronic …, 2021 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is associated with major healthcare and
socioeconomic burdens. International consortia recommend a personalized approach to …

Beyond dual bronchodilation–triple therapy, when and why

M Cazzola, P Rogliani, R Laitano… - … Journal of Chronic …, 2022 - Taylor & Francis
Although pharmacological treatment of COPD is codified in different guidelines and strategy
documents, there is abundant evidence of discrepancy between what they suggest and what …

[HTML][HTML] Single-inhaler triple vs single-inhaler dual therapy in patients with chronic obstructive pulmonary disease: a meta-analysis of randomized control trials

H Long, H Xu, JP Janssens, Y Guo - Respiratory Research, 2021 - Springer
Abstract Background In some RCTs comparing triple therapy with dual therapy in COPD,
there might be a bias resulting from the use of multiple inhaler devices. This meta-analysis …

[HTML][HTML] The impact of 52-week single inhaler device triple therapy versus dual therapy on the mortality of COPD patients: a systematic review and meta-analysis of …

CC Lai, CH Chen, KH Chen, CY Wang, TM Huang… - Life, 2022 - mdpi.com
There are more single inhaler device triple therapy available for COPD patients now.
However, the effect of long-term triple therapy fixed dose combination (FDC) on mortality …

Effectiveness of pulmonary rehabilitation in individuals with Chronic Obstructive Pulmonary Disease according to inhaled therapy: The Maugeri study

M Vitacca, M Paneroni, A Spanevello, P Ceriana… - Respiratory …, 2022 - Elsevier
Background and aim Real-life studies report discordant prescribing of inhaled triple therapy
(TT) among individuals with COPD. Guidelines recommend pulmonary rehabilitation (PR) …

Comparative effectiveness and safety of triple therapy and non-triple therapy interventions for COPD: an overview of systematic reviews

S Zhang, J Wang, X Li, H Zhang - Therapeutic Advances in …, 2024 - journals.sagepub.com
Background: Some systematic reviews (SRs) on triple therapy (consisting of long-acting β2-
agonist, long-acting muscarinic antagonist, and inhaled corticosteroid, LABA/LAMA/ICS) for …