How can electrospinning further service well for pharmaceutical researches?

DG Yu, J Zhou - Journal of Pharmaceutical Sciences, 2023 - Elsevier
The past two decades have witnessed the enormous success and progress of
electrospinning, as well as its broad and useful applications in pharmaceutics as a …

Twin screw melt granulation: a single step approach for developing self-emulsifying drug delivery system for lipophilic drugs

D Nyavanandi, P Mandati, S Narala, A Alzahrani… - Pharmaceutics, 2023 - mdpi.com
The current research aims to improve the solubility of the poorly soluble drug, ie, ibuprofen,
by developing self-emulsifying drug delivery systems (SEDDS) utilizing a twin screw melt …

[HTML][HTML] Self-nanomicellizing solid dispersion: A promising platform for oral drug delivery

W Chen, A Yan, T Sun, X Wang, W Sun… - Colloids and Surfaces B …, 2024 - Elsevier
Amorphous solid dispersion (ASD) has been widely used to enhance the oral bioavailability
of water-insoluble drugs for oral delivery because of its advantages of enhancing solubility …

Zwitterionic Surface Modification of Aldehydated Sulfobetaine Copolymers for the Formation of Bioinert Interfaces

YN Chou, MZ Ou - ACS Applied Polymer Materials, 2023 - ACS Publications
This research successfully developed a zwitterionic copolymer, poly (2-oxoethyl
methacrylate-co-sulfobetaine methacrylate) poly (OxMA-co-SBMA), in which the OxMA …

[HTML][HTML] Curcumin amorphous solid dispersions benefit from hydroxypropyl methylcellulose E50 to perform enhanced anti-inflammatory effects

J Zhang, X Shi, W Tao - International Journal of Biological Macromolecules, 2023 - Elsevier
The solubility and permeability enhancement of curcumin (Cur) is crucial for its manufacture
and application in medical field. Herein, Cur amorphous solid dispersions (ASDs) with …

Multi-functional Chitosan Polymeric Micelles for improving the oral bioavailability of Paclitaxel based on synergistic effect

W Zhang, Q Zhang, Y Yang, Y Chen, J Wei… - Drug Delivery and …, 2024 - Springer
A novel multi-functional micelle delivery system was developed for enhancing the oral
absorption of paclitaxel (PTX). The delivery carriers were constructed by modifying chitosan …

Optimization of O/W Emulsion Solvent Evaporation Method for Itraconazole Sustained Release Microspheres

W Wang, H Kojima, M Gao, X Yin… - Chemical and …, 2023 - jstage.jst.go.jp
Itraconazole, a commonly used antifungal drug in the clinic approved by US Food and Drug
Administration (FDA), has been gradually found to have anti-tumor, angiogenesis inhibition …

[HTML][HTML] 両親媒性リン脂質ポリマーを用いた難溶性薬物の可溶化

吉江健介, 石原一彦 - YAKUGAKU ZASSHI, 2023 - jstage.jst.go.jp
Most drug candidates developed in recent years are poorly water-soluble, which is a key
challenge in pharmaceutical science. Various solubilization methods have been …