Highly toxic metabolites of oxygen are generated normally by aerobic metabolism in most
cells, and this generation is often greatly increased in pathologic conditions. When this …

The inflammation produced by exposure to ultraviolet (UV) light has been well documented
clinically and histologically. However, the mechanisms by which mediators induce this …

Mature desiccation-tolerant (orthodox) seeds will retain viability for varying periods
depending upon the species and the storage conditions. A number of distinct but interacting …

Metabolic gradients exist in developing organisms and are believed to influence
development. It has been postulated that the effects of these gradients on development …

Oxygen is essential to our living, but it has an undesirable effect known as an oxygen toxicity
through the formation of active oxygen species [1]. There are a large number of endogenous …

To determine if some specific “preparation for birth” occurs in the developing lung to help
assure its successful adaptation to a comparatively O 2-rich world at birth, we measured the …

We examined the chronology of development of both fetal lung antioxidant enzymes
(superoxide dismutase, catalase, and glutathione peroxidase) and disaturated …

Reactive oxygen species (ROS) have been implicated in the pathogenesis of many clinical
disorders such as adult respiratory distress syndrome, ischemia-reperfusion injury …

The current hypothesis for the damage caused to mammalian tisues by hyperoxia is that
oxygen radicals and related reactive oxygen metabolites are formed at rates which exceed …

Living creatures find, in molecular oxygen, both benefit and detriment. Thus, while being
useful to aerobes as an electron sink for energy-yielding reactions and as a reagent for …