Using a therapeutic strategy that is free from traditional diagnostic labels and based on the
identification of “treatable traits”(TTs), which are influential in clinical presentations in each …

Classically, the effects elicited by corticosteroids (CS) are mediated by the binding and
activation of cytosolic glucocorticoid receptors (GR). However, several of the non-genomic …

Although pharmacological treatment of COPD is codified in different guidelines and strategy
documents, there is abundant evidence of discrepancy between what they suggest and what …

Isolated airway smooth muscle has been extensively investigated since 1840 to understand
the pharmacology of airway diseases. There has often been poor predictability from murine …

Introduction Solid pharmacological rationale and clinical evidence support the use of a
combination of an inhaled corticosteroid (ICS), a long-acting β2-agonist, and a long-acting …

The BNT162b2 COVID-19 vaccine is composed of lipid-nanoparticles (LNP) containing the
mRNA that encodes for SARS-CoV-2 spike glycoprotein. Bronchospasm has been reported …

Airway inflammation is crucial in the pathogenesis of many respiratory diseases, including
chronic obstructive pulmonary disease (COPD) and asthma. Current evidence supports the …

На основании анализа результатов рандомизированных контролируемых
исследований, а также клинико-функционального и экспериментального исследования …