Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms

YQ He, CC Zhou, LY Yu, L Wang, J Deng… - Pharmacological …, 2021 - Elsevier
Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …

Recent advances in pathophysiology and management of transient tachypnea of newborn

Z Alhassen, P Vali, L Guglani… - Journal of …, 2021 - nature.com
Transient tachypnea of newborn (TTN) results from failure of the newborn to effectively clear
the fetal lung fluid soon after birth. TTN represents the most common etiology of respiratory …

Pulmonary edema in COVID-19 patients: mechanisms and treatment potential

X Cui, W Chen, H Zhou, Y Gong, B Zhu, X Lv… - Frontiers in …, 2021 - frontiersin.org
COVID-19 mortality is primarily driven by abnormal alveolar fluid metabolism of the lung,
leading to fluid accumulation in the alveolar airspace. This condition is generally referred to …

Anatomical basis and physiological role of cerebrospinal fluid transport through the murine cribriform plate

JN Norwood, Q Zhang, D Card, A Craine, TM Ryan… - Elife, 2019 - elifesciences.org
Cerebrospinal fluid (CSF) flows through the brain, transporting chemical signals and
removing waste. CSF production in the brain is balanced by a constant outflow of CSF, the …

Signaling mechanisms and pharmacological modulators governing diverse aquaporin functions in human health and disease

K Wagner, L Unger, MM Salman, P Kitchen… - International Journal of …, 2022 - mdpi.com
The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

Vascular inflammation is associated with loss of aquaporin 1 expression on endothelial cells and increased fluid leakage in SARS-CoV-2 infected golden Syrian …

L Allnoch, G Beythien, E Leitzen, K Becker, FJ Kaup… - Viruses, 2021 - mdpi.com
Vascular changes represent a characteristic feature of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) infection leading to a breakdown of the vascular barrier and …

Alveolar macrophages: Achilles' heel of SARS-CoV-2 infection

Z Wang, S Li, B Huang - Signal Transduction and Targeted Therapy, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused more than 6.3
million deaths to date. Despite great efforts to curb the spread of severe acute respiratory …

Towards green 3D-microfabrication of Bio-MEMS devices using ADEX dry film photoresists

MM Roos, A Winkler, M Nilsen, SB Menzel… - International Journal of …, 2022 - Springer
Current trends in miniaturized diagnostics indicate an increasing demand for large
quantities of mobile devices for health monitoring and point-of-care diagnostics. This comes …

Mechanism of multi-organ injury in experimental COVID-19 and its inhibition by a small molecule peptide

MJ Paidas, N Sampath, EA Schindler… - Frontiers in …, 2022 - frontiersin.org
Severe disease from SARS-CoV-2 infection often progresses to multi-organ failure and
results in an increased mortality rate amongst these patients. However, underlying …

P2 purinergic signaling in the distal lung in health and disease

E Wirsching, M Fauler, G Fois, M Frick - International journal of molecular …, 2020 - mdpi.com
The distal lung provides an intricate structure for gas exchange in mammalian lungs.
Efficient gas exchange depends on the functional integrity of lung alveoli. The cells in the …