Myeloid neoplasms and acute leukemias derive from the clonal expansion of hematopoietic
cells driven by somatic gene mutations. Although assessment of morphology plays a crucial …

Cytogenetics has long represented a critical component in the clinical evaluation of
hematologic malignancies. Chromosome banding studies provide a simultaneous snapshot …

Acute myeloid leukemia (AML) is a genetically heterogeneous clonal disorder characterized
by the accumulation of acquired somatic genetic alterations in hematopoietic progenitor …

Genomic structural variations in myeloid, lymphoid, and plasma cell neoplasms can provide
key diagnostic, prognostic, and therapeutic information while elucidating the underlying …

Auch im Zeitalter der molekularen Medizin fusst die Diagnostik von myelodysplastischen
Syndromen (MDS) auf den visuellen Methoden der Knochenmarksmorphologie und der …

Structural variations (SVs) play a key role in the pathogenicity of hematological
malignancies. Optical genome mapping (OGM) is an emerging technology that enables …

Pre-analytical factors in molecular oncology diagnostics are reviewed. Issues around
sample collection, storage, and transport that might affect the stability of nucleic acids and …

Diagnosis and treatment of hematological malignancies, a diverse category of tumors that
begin in the blood and bone marrow, are extremely difficult. Our knowledge of these …

Миелодиспластические синдромы (МДС) представляют собой гетерогенную группу
заболеваний системы крови опухолевой природы, в основе которых лежит поражение …