Circulating miRNA analysis for cancer diagnostics and therapy
Successful treatment of cancer depends on early diagnosis and effective monitoring of
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …
Considerations and suggestions for the reliable analysis of miRNA in plasma using qRT-PCR
E Ban, EJ Song - Genes, 2022 - mdpi.com
MicroRNAs (miRNAs) are promising molecules that can regulate gene expression, and their
expression level and type have been associated with early diagnosis, targeted therapy, and …
expression level and type have been associated with early diagnosis, targeted therapy, and …
Serum NFL discriminates Parkinson disease from atypical parkinsonisms
TM Marques, A van Rumund, P Oeckl, HB Kuiperij… - Neurology, 2019 - AAN Enterprises
Objective To investigate the diagnostic value of serum neurofilament light chain (NFL) in
patients with clear signs of parkinsonism but whose specific diagnosis was yet uncertain …
patients with clear signs of parkinsonism but whose specific diagnosis was yet uncertain …
Circulating exosome‐like vesicle and skeletal muscle microRNAs are altered with age and resistance training
D Xhuti, MI Nilsson, K Manta… - The Journal of …, 2023 - Wiley Online Library
The age‐related loss of skeletal muscle mass and functionality, known as sarcopenia, is a
critical risk factor for morbidity and all‐cause mortality. Resistance exercise training (RET) is …
critical risk factor for morbidity and all‐cause mortality. Resistance exercise training (RET) is …
Breast cancer-delivered exosomal miRNA as liquid biopsy biomarkers for metastasis prediction: a focus on translational research with clinical applicability
O Baldasici, V Pileczki, D Cruceriu, LI Gavrilas… - International Journal of …, 2022 - mdpi.com
Metastasis represents the most important cause of breast cancer-associated mortality. Even
for early diagnosed stages, the risk of metastasis is significantly high and predicts a grim …
for early diagnosed stages, the risk of metastasis is significantly high and predicts a grim …
Sedentary and trained older men have distinct circulating exosomal microRNA profiles at baseline and in response to acute exercise
Exercise has multi-systemic benefits and attenuates the physiological impairments
associated with aging. Emerging evidence suggests that circulating exosomes mediate …
associated with aging. Emerging evidence suggests that circulating exosomes mediate …
Challenges in using circulating micro-RNAs as biomarkers for cardiovascular diseases
K Felekkis, C Papaneophytou - International Journal of Molecular …, 2020 - mdpi.com
Micro-RNAs (miRNAs) play a pivotal role in the development and physiology of the
cardiovascular system while they have been associated with multiple cardiovascular …
cardiovascular system while they have been associated with multiple cardiovascular …
A systematic way to infer the regulation relations of miRNAs on target genes and critical miRNAs in cancers
P Xu, Q Wu, J Yu, Y Rao, Z Kou, G Fang, X Shi… - Frontiers in …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are a class of important non-coding RNAs, which play important roles
in tumorigenesis and development by targeting oncogenes or tumor suppressor genes. One …
in tumorigenesis and development by targeting oncogenes or tumor suppressor genes. One …
Development of circulating microRNA-based biomarkers for medical decision-making: a friendly reminder of what should NOT be done
Circulating cell-free microRNAs (miRNAs) represent a major reservoir for biomarker
discovery. Unfortunately, their implementation in clinical practice is limited due to a profound …
discovery. Unfortunately, their implementation in clinical practice is limited due to a profound …
Circulating MicroRNAs and extracellular vesicle-derived MicroRNAs as predictors of functional recovery in ischemic stroke patients: a systematic review and meta …
CC Burlacu, D Ciobanu, AV Badulescu… - International Journal of …, 2022 - mdpi.com
Stroke accounts for the second leading cause of death and a major cause of disability, with
limited therapeutic strategy in both the acute and chronic phases. Blood-based biomarkers …
limited therapeutic strategy in both the acute and chronic phases. Blood-based biomarkers …