Tuberculosis (TB) kills more individuals in the world than any other disease, and a threat
made direr by the coverage of drug-resistant strains of Mycobacterium tuberculosis (Mtb) …

Induction of Th1 (cell-mediated) immunity and associated production of IFN-γ by CD4+ T
cells has been widely used as a marker of protective immunity against tuberculosis (TB) …

Many pathogenic viral pandemics have caused threats to global health; the COVID-19
pandemic is the latest. Its transmission is growing exponentially all around the globe, putting …

Traditional vaccine development against infectious diseases has been guided by the
overarching aim to generate efficacious vaccines normally indicated by an antibody and/or …

Tuberculosis (TB) is an infectious disease that mainly affects the lungs and spreads to other
organs of the body through the haematogenous route. It is one of the ten major causes of …

Effective control of Mycobacterium tuberculosis is a global necessity. In 2015, tuberculosis
(TB) caused more deaths than HIV. Considering the increasing prevalence of multi-drug …

Tuberculosis (TB), an infectious disease, has been a leading cause of morbidity and
mortality for decades. The causative agent of TB is the Mycobacterium tuberculosis (Mtb) …

Infection by Mycobacterium tuberculosis (Mtb) remains a major global concern and the
available Bacillus Calmette-Guerin (BCG) vaccine is poorly efficacious in adults. Therefore …

Tuberculosis (TB) is one of the deadliest infectious diseases worldwide and is caused by
Mycobacterium tuberculosis (Mtb). An effective vaccine to prevent TB is considered the most …

Chronic pulmonary inflammation marked predominantly by CD4+ IFN-γ+ cells is the
hallmark of tuberculosis pathogenesis in immunocompetent adults, who are substantially …