It has long been presumed that after leaving the germinal centers (GCs), memory B cells
colonize the marginal zone or join the recirculating pool. Here we demonstrate the …

Severe forms of pneumococcal meningitis, bacteraemia and pneumonia result in more than
1 million deaths each year despite the widespread introduction of carbohydrate-protein …

Germinal center (GC) B cells and T follicular helper (T FH) cells interact in the production of
high-affinity long-lived plasma cells (PCs) and memory B cells, although the mechanisms …

Understanding how memory B cells are induced and relate to long-lived plasma cells is
important for vaccine development. Immunity to oral vaccines has been considered short …

Autoimmune diseases and other inflammatory conditions are characterized by large
lymphocytic tissue infiltrates in which T and B cells can be found in close contact. Here …

Despite their critical role in long-term immunity, the life span of individual memory B cells
remains poorly defined. Using a tetracycline-regulated pulse-chase system, we measured …

Age‐associated B cells (ABC), a novel subset of activated B cells defined by CD11b and
CD11c expression, have been linked with both protective anti‐viral responses and the …

Chemokine-dependent localization of specific B cell subsets within the immune
microarchitecture is essential to ensure successful cognate interactions. Although cognate …

Whereas gut IgA responses to the microbiota may be multi-centered and diverse, little is
known about IgA responses to T-cell-dependent antigens following oral immunizations …

Immunological memory has long considered to be harbored in B cells that express high-
affinity class-switched IgG. IgM-positive memory B cells can also be generated following …