Nucleoid-associated protein HU: A lilliputian in gene regulation of bacterial virulence

P Stojkova, P Spidlova, J Stulik - Frontiers in cellular and infection …, 2019 - frontiersin.org
Nucleoid-associated proteins belong to a group of small but abundant proteins in bacterial
cells. These transcription regulators are responsible for many important cellular processes …

Transcription of bacterial chromatin

BA Shen, R Landick - Journal of molecular biology, 2019 - Elsevier
Decades of research have probed the interplay between chromatin (genomic DNA
associated with proteins and RNAs) and transcription by RNA polymerase (RNAP) in all …

Single-stranded DNA recruitment mechanism in replication origin unwinding by DnaA initiator protein and HU, an evolutionary ubiquitous nucleoid protein

R Yoshida, S Ozaki, H Kawakami… - Nucleic acids …, 2023 - academic.oup.com
The Escherichia coli replication origin oriC contains the initiator ATP-DnaA-Oligomerization
Region (DOR) and its flanking duplex unwinding element (DUE). In the Left-DOR subregion …

Pangenome-level analysis of nucleoid-associated proteins in the Acidithiobacillia class: insights into their functional roles in mobile genetic elements biology

S Beard, A Moya-Beltrán, D Silva-García… - Frontiers in …, 2023 - frontiersin.org
Mobile genetic elements (MGEs) are relevant agents in bacterial adaptation and
evolutionary diversification. Stable appropriation of these DNA elements depends on host …

Time-restricted feeding induces Lactobacillus- and Akkermansia-specific functional changes in the rat fecal microbiota

A Palomba, A Tanca, M Abbondio, R Sau… - NPJ biofilms and …, 2021 - nature.com
Diet is a key factor influencing gut microbiota (GM) composition and functions, which in turn
affect host health. Among dietary regimens, time-restricted (TR) feeding has been …

Bacteriophage protein Gp46 is a cross-species inhibitor of nucleoid-associated HU proteins

P Zhang, X Zhao, Y Wang, K Du… - Proceedings of the …, 2022 - National Acad Sciences
The architectural protein histone-like protein from Escherichia coli strain U93 (HU) is the
most abundant bacterial DNA binding protein and highly conserved among bacteria and …

[HTML][HTML] Distribution and phasing of sequence motifs that facilitate CRISPR adaptation

A Santiago-Frangos, M Buyukyoruk, T Wiegand… - Current Biology, 2021 - cell.com
CRISPR-associated proteins (Cas1 and Cas2) integrate foreign DNA at the" leader" end of
CRISPR loci. Several CRISPR leader sequences are reported to contain a binding site for a …

Epigallocatechin Gallate with Potent Anti-Helicobacter pylori Activity Binds Efficiently to Its Histone-like DNA Binding Protein

R Raj, N Agarwal, S Raghavan, T Chakraborti… - ACS …, 2021 - ACS Publications
Helicobacter pylori (H. pylori)—a human gastric pathogen—forms a major risk factor for the
development of various gastric pathologies such as chronic inflammatory gastritis, peptic …

[HTML][HTML] The bacterial chromatin protein HupA can remodel DNA and associates with the nucleoid in Clostridium difficile

AMO Paiva, AH Friggen, L Qin, R Douwes… - Journal of molecular …, 2019 - Elsevier
The maintenance and organization of the chromosome plays an important role in the
development and survival of bacteria. Bacterial chromatin proteins are architectural proteins …

The structural basis of African swine fever virus pA104R binding to DNA and its inhibition by stilbene derivatives

R Liu, Y Sun, Y Chai, S Li, S Li… - Proceedings of the …, 2020 - National Acad Sciences
African swine fever virus (ASFV) is a highly contagious nucleocytoplasmic large DNA virus
(NCLDV) that causes nearly 100% mortality in swine. The development of effective vaccines …