Microbial underdogs: exploring the significance of low-abundance commensals in host-microbe interactions

G Han, S Vaishnava - Experimental & Molecular Medicine, 2023 - nature.com
Our understanding of host-microbe interactions has broadened through numerous studies
over the past decades. However, most investigations primarily focus on the dominant …

Oral complications from oropharyngeal cancer therapy

V Sankar, Y Xu - Cancers, 2023 - mdpi.com
Simple Summary Although oropharyngeal cancers are increasing in incidence, more
patients are surviving their cancer therapy. Once a patient has completed their …

Candida albicans and Antifungal Peptides

CG Freitas, MS Felipe - Infectious Diseases and Therapy, 2023 - Springer
Candida albicans, a ubiquitous opportunistic fungal pathogen, plays a pivotal role in human
health and disease. As a commensal organism, it normally resides harmlessly within the …

A Brg1-Rme1 circuit in Candida albicans hyphal gene regulation

MJ Kim, M Cravener, N Solis, SG Filler, AP Mitchell - mBio, 2024 - journals.asm.org
Major Candida albicans virulence traits include its ability to make hyphae, to produce a
biofilm, and to damage host cells. These traits depend upon expression of hypha-associated …

The Hog1 MAPK substrate governs Candida glabrata-epithelial cell adhesion via the histone H2A variant

MS Sahu, R Purushotham, R Kaur - Plos Genetics, 2024 - journals.plos.org
CgHog1, terminal kinase of the high-osmolarity glycerol signalling pathway, orchestrates
cellular response to multiple external stimuli including surplus-environmental iron in the …

Disruption to de novo uridine biosynthesis alters β-1,3-glucan masking in Candida albicans

MM Mangrum, AK Vogel, AS Wagner, AE King, J Miao… - mSphere, 2024 - journals.asm.org
The uridine derivatives UDP-glucose and UDP-N-acetylglucosamine are important for cell
wall construction as they are the precursors for the synthesis of β-1, 3-glucan and chitin …

[HTML][HTML] Neonatal Gut Mycobiome: Immunity, Diversity of Fungal Strains, and Individual and Non-Individual Factors

A Mpakosi, R Sokou, M Theodoraki… - Life, 2024 - ncbi.nlm.nih.gov
The human gastrointestinal ecosystem, or microbiome (comprising the total bacterial
genome in an environment), plays a crucial role in influencing host physiology, immune …

The inhibitory effects of carvacrol, nystatin, and their combination on oral candidiasis isolates

SSH Balef, SS Hosseini, N Asgari, A Sohrabi… - BMC Research …, 2024 - Springer
Background Candida, a common oral microbiota, can cause opportunistic fungal infections.
With rising Candida infections and limited effective antifungals, new treatments are needed …

Licochalcone A Protects Vaginal Epithelial Cells Against Candida albicans Infection Via the TLR4/NF-κB Signaling Pathway

W Li, Y Yin, T Li, Y Wang, W Shi - Journal of Microbiology, 2024 - Springer
Vulvovaginal candidiasis (VVC) is a prevalent condition affecting a significant portion of
women worldwide. Licochalcone A (LA), a natural compound with diverse biological …

Выявление закономерностей влияния микробиоты на патогенетические механизмы развития системной красной волчанки

АА Шайхутдинова, ДА Бурбеза… - Современная …, 2024 - mrj.ima-press.net
Аннотация Системная красная волчанка (СКВ)–сложное, многофакторное
аутоиммунное заболевание, характеризующееся мультисистемным поражением …