Actions of symbiotic gut microbiota are in dynamic balance with the host's organism to
maintain homeostasis. Many different factors have an impact on this relationship, including …

Introduction Obesity is a disorder characterized by a disproportionate increase in body
weight in relation to height, mainly due to the accumulation of fat, and is considered a …

Indole and its derivatives are widespread across different life forms, functioning as signalling
molecules in prokaryotes and with more diverse roles in eukaryotes. A majority of indoles …

Recent evidence suggests that gut bacteria-derived metabolites interact with the
cardiovascular system and alter blood pressure (BP) in mammals. Here, we evaluated the …

Background Tryptophan (Trp) metabolites from intestinal bacteria (indole, indole acetic acid
[IAA] and indole propionic acid [IPA]), and the Trp metabolite kynurenine (Kyn) from the …

Metabolomics offers new methods to identify biomarkers for oocyte and embryo quality, and
for a better understanding of the physiopathology of infertility. We review the latest findings …

Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder in women of
reproductive age. Some studies have investigated metabolic alterations in plasma and …

Tryptophan (TRP) and its indole metabolites exhibit numerous biological effects, especially
their antioxidant properties. This study used untargeted metabolomics in conjunction with …

Obesity exerts negative effects on the metabolic homeostasis of cells in various tissues, but
how it influences ovum metabolism is not fully understood. Previous studies demonstrate …

Extremes in body condition reduce fertility and overall productivity in beef cattle herds, due
in part to altered systemic metabolic conditions that influence the intrafollicular and uterine …