Big data and ophthalmic research

A Clark, JQ Ng, N Morlet, JB Semmens - survey of ophthalmology, 2016 - Elsevier
Large population-based health administrative databases, clinical registries, and data
linkage systems are a rapidly expanding resource for health research. Ophthalmic research …

Cardiovascular and respiratory considerations with pharmacotherapy of glaucoma and ocular hypertension

JA Han, WH Frishman, SW Sun, PM Palmiero… - Cardiology in …, 2008 - journals.lww.com
Glaucoma and ocular hypertension are highly prevalent conditions in individuals over the
age of 40 and are commonly seen together in patients with cardiovascular disease. Many of …

Randomized trial of brinzolamide/brimonidine versus brinzolamide plus brimonidine for open-angle glaucoma or ocular hypertension

SA Gandolfi, J Lim, AC Sanseau, JC Parra Restrepo… - Advances in …, 2014 - Springer
Introduction Fixed-combination intraocular pressure (IOP)—lowering medications simplify
treatment regimens for patients requiring 2 ocular hypotensive agents to maintain sufficiently …

Managing glaucoma in those with co-morbidity: not as easy as it seems

EE Roughead, LM Kalisch, NL Pratt, G Killer… - Ophthalmic …, 2012 - Taylor & Francis
Purpose: To identify the extent of use of medicines recommended to be used with caution in
glaucoma patients with specified comorbidities and to determine evidence of associated …

Adjunctive therapy patterns in glaucoma patients using prostaglandin analogs

JK Schmier, CK Hulme-Lowe, DW Covert - Clinical Ophthalmology, 2014 - Taylor & Francis
Purpose To analyze patterns of use of adjunctive therapies among new initiators of topical
prostaglandin analogs (PGAs) in a managed care population. Methods The study cohort …

Use of glaucoma medications: state of the science and directions for observational research

VH Lu, I Goldberg, CY Lu - American journal of ophthalmology, 2010 - Elsevier
PURPOSE: To summarize observational studies that focus on the use of glaucoma
medications and to identify gaps in knowledge to guide future investigation. DESIGN …

Resource utilization among glaucoma patients in the UK treated with beta-blocker and Non-Beta-Blocker adjunctive therapy: a retrospective cohort analysis

A Viswanathan, C Spera, A Mullins, D Covert… - Advances in …, 2017 - Springer
Introduction Few studies have examined outcomes and potential complications among
glaucoma patients who are prescribed topical beta-blockers. This study examined resource …

Changing initial glaucoma medical therapy increases healthcare resource utilization

MGJ Trese, AW Lewis, TS Blachley… - Journal of Ocular …, 2017 - liebertpub.com
Purpose: To determine the frequency and economic impact of changing initial glaucoma
therapy for patients with newly diagnosed open-angle glaucoma (OAG) or ocular …

Association between topical beta-blockers and risks of cardiovascular and respiratory disease in patients with glaucoma: a retrospective cohort study

HY Chen, WC Huang, CL Lin, CH Kao - BMJ open, 2020 - bmjopen.bmj.com
Objective To determine if topical beta-blocker use is associated with increased risks of
cardiovascular and respiratory diseases in patients with glaucoma. Setting A retrospective …

Prescription of ocular β-blockers in patients with obstructive pulmonary disease: Does a central electronic medical record make a difference?

S Vinker, I Kaiserman, DA Waitman, S Blackman… - Clinical drug …, 2006 - Springer
Objectives: Topical β-blockers are contraindicated in obstructive pulmonary diseases
(OPDs). In this study we aimed to evaluate through central or local electronic medical …