Isoorientin reverses lung cancer drug resistance by promoting ferroptosis via the SIRT6/Nrf2/GPX4 signaling pathway
S Feng, Y Li, H Huang, H Huang, Y Duan… - European Journal of …, 2023 - Elsevier
Cisplatin, or DDP, is a highly successful and well-known chemotherapy drug used to treat
cancer. Acquired resistance to chemotherapy is a major clinical concern, yet the …
cancer. Acquired resistance to chemotherapy is a major clinical concern, yet the …
Isoorientin attenuates doxorubicin-induced cardiac injury via the activation of MAPK, Akt, and Caspase-dependent signaling pathways
S Li, H Liu, Z Lin, Z Li, Y Chen, B Chen, L Huang, X Lin… - Phytomedicine, 2022 - Elsevier
Background Chemotherapy drugs especially anthracyclines are widely used in the treatment
of hematological malignancies and solid tumors. However, their clinical application is limited …
of hematological malignancies and solid tumors. However, their clinical application is limited …
Effects of natural flavonoid isoorientin on growth performance and gut microbiota of mice
L Yuan, X Li, S He, C Gao, C Wang… - Journal of agricultural …, 2018 - ACS Publications
Isoorientin (ISO) is a natural flavonoid, which is a 6-C-glucoside of luteolin, and has been
demonstrated to possess multiple biological properties. In this study, the effects of ISO on the …
demonstrated to possess multiple biological properties. In this study, the effects of ISO on the …
Isoorientin prevents hyperlipidemia and liver injury by regulating lipid metabolism, antioxidant capability, and inflammatory cytokine release in high-fructose-fed mice
L Yuan, X Han, W Li, D Ren, X Yang - Journal of agricultural and …, 2016 - ACS Publications
Isoorientin (ISO), a natural flavonoid, has been found to have multiple biological properties.
In the present study, obese mice with high-fructose (HF)-induced liver injury were used to …
In the present study, obese mice with high-fructose (HF)-induced liver injury were used to …
Cyanidin-3-glucoside prevents hydrogen peroxide (H2O2)-induced oxidative damage in HepG2 cells
J Tan, P Li, H Xue, Q Li - Biotechnology Letters, 2020 - Springer
Objective The aim of this study is to evaluate the cytoprotection and potential molecular
mechanisms of cyanidin-3-glucoside (C3G) on hydrogen peroxide (H 2 O 2)-induced …
mechanisms of cyanidin-3-glucoside (C3G) on hydrogen peroxide (H 2 O 2)-induced …
Chemical profiles, antioxidant and anti-obesity effects of extract of Bambusa textilis McClure leaves
Abstract Bambusa textilis McClure (Bambusoideae) is a valuable bamboo species widely
distributed in southern China. The methanolic extract of B. textilis leaves was examined for …
distributed in southern China. The methanolic extract of B. textilis leaves was examined for …
Effect of isoorientin on intracellular antioxidant defence mechanisms in hepatoma and liver cell lines
L Yuan, J Wang, W Wu, Q Liu, X Liu - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Isoorientin (ISO) is considered one of the most important flavonoid-like compounds
responsible for health benefits, including the prevention of liver damage as well as …
responsible for health benefits, including the prevention of liver damage as well as …
[HTML][HTML] Tea polyphenols ameliorate hydrogen peroxide-and constant darkness-triggered oxidative stress via modulating the Keap1/Nrf2 transcriptional signaling …
Tea polyphenols, which are natural plant flavonoids found in the leaves of tea plants,
possess bioactivities that affect the pathogenesis of several chronic diseases. However, the …
possess bioactivities that affect the pathogenesis of several chronic diseases. However, the …
Distribution of four bioactive flavonoids in maize tissues of five varieties and correlation with expression of the biosynthetic genes
Flavonoids are characteristic in maize and have diverse biological functions. C-
Glycosylflavones are neuroprotective against β-amyloid-induced tau hyperphosphorylation …
Glycosylflavones are neuroprotective against β-amyloid-induced tau hyperphosphorylation …
Chemical constituents of Triticum aestivum and their effects on adipogenic differentiation of 3T3-L1 preadipocytes
BTT Luyen, NP Thao, BH Tai, JY Lim, HH Ki… - Archives of pharmacal …, 2015 - Springer
In this report, we investigated the anti-obesity effect of wheat sprouts and their component
compounds. Twenty compounds (1–20) were isolated from Triticum aestivum. Among them …
compounds. Twenty compounds (1–20) were isolated from Triticum aestivum. Among them …