Granulomas in parasitic diseases: the good and the bad
Parasitic diseases affect more than one billion people worldwide, and most of them are
chronic conditions in which the treatment and prevention are difficult. The appearance of …
chronic conditions in which the treatment and prevention are difficult. The appearance of …
Schistosoma and Leishmania: An Untold Story of Coinfection
GMA Camelo, JKAO Silva, SM Geiger… - Tropical Medicine and …, 2023 - mdpi.com
A remarkable characteristic of infectious diseases classified as Neglected Tropical Diseases
(NTDs) is the fact that they are mostly transmitted in tropical and subtropical regions with …
(NTDs) is the fact that they are mostly transmitted in tropical and subtropical regions with …
Leishmania infantum-induced primary and challenge infections in rhesus monkeys (Macaca mulatta): a primate model for visceral leishmaniasis
R Porrozzi, MS Pereira, A Teva… - Transactions of the …, 2006 - academic.oup.com
Visceral leishmaniasis (VL) was experimentally induced in rhesus macaques (Macaca
mulatta) by intravenously inoculating 2× 107 amastigotes/kg of body weight of Leishmania …
mulatta) by intravenously inoculating 2× 107 amastigotes/kg of body weight of Leishmania …
Non-human primates and Leishmania immunity
S André, V Rodrigues, M Picard, R Silvestre… - Cytokine: X, 2020 - Elsevier
In the context of infectious diseases, non-human primates (NHP) provide the best animal
models of human diseases due to the close phylogenetic relationship and the similar …
models of human diseases due to the close phylogenetic relationship and the similar …
Dynamics of immune granuloma formation in a Leishmania braziliensis‐induced self‐limiting cutaneous infection in the primate Macaca mulatta
C Souza‐Lemos, SN de‐Campos… - The Journal of …, 2008 - Wiley Online Library
In order to unravel the physiopathology of leishmaniasis in humans, it is necessary to better
understand how Leismania are able to survive for years within immunologically active …
understand how Leismania are able to survive for years within immunologically active …
Different isolates from Leishmania braziliensis complex induce distinct histopathological features in a murine model of infection
CG Pereira, ALN Silva, P de Castilhos… - Veterinary …, 2009 - Elsevier
The aim of this study was to evaluate the histopathological features in tissues of mice
infected by human isolates (I, II, and III) or the reference M2903 strain of Leishmania …
infected by human isolates (I, II, and III) or the reference M2903 strain of Leishmania …
The utility of rhesus monkey (Macaca mulatta) and other non-human primate models for preclinical testing of Leishmania candidate vaccines
G Grimaldi Jr - Memorias Do Instituto Oswaldo Cruz, 2008 - SciELO Brasil
Leishmaniasis causes significant morbidity and mortality, constituting an important global
health problem for which there are few effective drugs. Given the urgent need to identify a …
health problem for which there are few effective drugs. Given the urgent need to identify a …
In situ characterization of the granulomatous immune response with time in nonhealing lesional skin of Leishmania braziliensis-infected rhesus macaques (Macaca …
C Souza-Lemos, SN de-Campos, A Teva… - Veterinary immunology …, 2011 - Elsevier
We have recently introduced a macaque (Macaca mulatta) model of Leishmania braziliensis-
induced self-healing cutaneous leishmaniasis in which the T cell-mediated inflammatory …
induced self-healing cutaneous leishmaniasis in which the T cell-mediated inflammatory …
Leishmania (Viannia): genetic analysis of cutaneous and mucosal strains isolated from the same patient
P Cuervo, E Cupolillo, N Nehme, V Hernandez… - Experimental …, 2004 - Elsevier
Ten pairs of Leishmania (Viannia) strains isolated from mucosal and cutaneous lesions of
the same patient were analyzed genotypically in order to determine whether populations …
the same patient were analyzed genotypically in order to determine whether populations …
Systemic and compartmentalised immune responses in a Leishmania braziliensis-macaque model of self-healing cutaneous leishmaniasis
SN De-Campos, C Souza-Lemos, A Teva… - Veterinary immunology …, 2010 - Elsevier
We have recently introduced a macaque (Macaca mulatta) model of Leishmania braziliensis-
induced chronic granulomatous cutaneous lesions affecting the nasal mucosa. Using an L …
induced chronic granulomatous cutaneous lesions affecting the nasal mucosa. Using an L …