Dopaminergic neurons in the midbrain are of particular interest due to their role in diseases
such as Parkinson's disease and schizophrenia. Genetic variation between individuals can …

目的研究昆明小鼠对不同剂量可卡因的敏感度, 为昆明小鼠在神经科学领域的应用,
制别是可卡因成瘾的研究提供参考. 方法同龄(8~ 12 周) 的雄性昆明小鼠 …

Palatable food is known for its ability to enhance reinforcing responses. Studies have
suggested a circadian variation in both drug and natural reinforcement, with each following …

Rationale Synthetic phenethylamine (PEA) analogs, such as β-methylphenethylamine
(BMPEA) and N, α-diethylphenethylamine (DEPEA), are often found in dietary supplements …

Dyadic physical social interaction influences cocaine‐seeking behaviour, although whether
limited sexual cues (LSC) from an opposite‐sex partner influence the behavioural …

The Na+-dependent dopamine transporter (DAT) is primarily responsible for regulating free
dopamine (DA) concentrations in the brain by participating in the majority of DA uptake; …

Background Developmental stress has been hypothesised to interact with genetic
predisposition to increase the risk of developing substance use disorders. Here we have …

Relapse is highly prevalent after detoxification and depression. Due to the advantages of
venlafaxine compared with other antidepressants, it is expected that venlafaxine …

Psychotic disorders represent a severe category of mental disorders affecting about one
percent of the population. Individuals experience a loss or distortion of contact with reality …

The cues associated with drug of abuse are one of the reasons that trigger drug seeking and
relapse even after a long abstinence. Pre-clinical studies have focused on such Pavlovian …