Considerations for cannabinoids in perioperative care by anesthesiologists

K Laudanski, J Wain - Journal of Clinical Medicine, 2022 - mdpi.com
Increased usage of recreational and medically indicated cannabinoid compounds has been
an undeniable reality for anesthesiologists in recent years. These compounds' complicated …

The role of TRPV1 in RA pathogenesis: worthy of attention

Y Qu, Y Fu, Y Liu, C Liu, B Xu, Q Zhang… - Frontiers in …, 2023 - frontiersin.org
Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a Ca2+
permeable, non-selective cation channel that is found primarily in sensory nerve fibres …

Orthodontic force-induced oxidative stress in the periodontal tissue and dental pulp elicits nociception via activation/sensitization of TRPA1 on nociceptive fibers

A Morii, Y Miyamura, MI Sago, M Mizuhara… - Free radical Biology and …, 2020 - Elsevier
Orthodontic patients complain of pain for the first few days after insertion of appliances.
Mechanical force has been reported to produce oxidants in periodontal ligament (PDL) cells …

TRPV1 and TRPV1-expressing nociceptors mediate orofacial pain behaviors in a mouse model of orthodontic tooth movement

S Wang, M Kim, Z Ali, K Ong, EK Pae… - Frontiers in …, 2019 - frontiersin.org
Orthodontic force produces mechanical irritation and inflammation in the periodontium,
which is inevitably accompanied by pain. Despite its prevalence, treatment of orthodontic …

Transient receptor potential Vanilloid 1-based gene therapy alleviates orthodontic pain in rats

R Guo, Y Zhou, H Long, D Shan, J Wen, H Hu… - International journal of …, 2019 - nature.com
Orthodontic pain that is induced by tooth movement is an important sequela of orthodontic
treatment and has a significant effect on patient quality of life. Studies have shown that the …

17β-Estradiol exacerbated experimental occlusal interference-induced chronic masseter hyperalgesia by increasing the neuronal excitability and TRPV1 function of …

Y Liu, XX Xu, Y Cao, SY Mo, SS Bai, YY Fan… - International Journal of …, 2021 - mdpi.com
Pain symptoms in temporomandibular disorders (TMD) predominantly affect reproductive
women, suggesting that estrogen regulates pain perception. However, how estrogen …

Modulation of excitatory synaptic transmissions by TRPV1 in the spinal trigeminal subnucleus caudalis neurons of neuropathic pain rats

M Tamada, Y Ohi, D Kodama, K Miyazawa… - European journal of …, 2021 - Elsevier
The present study examined contribution of the transient receptor potential vanilloid 1
channel (TRPV1) to the chronic orofacial pain. Bilateral partial nerve ligation (PNL) of the …

Molecular mechanism in trigeminal nerve and treatment methods related to orthodontic pain

Z Tang, J Zhou, H Long, Y Gao, Q Wang… - Journal of Oral …, 2022 - Wiley Online Library
Background Orthodontic treatment is the main treatment approach for malocclusion.
Orthodontic pain is an inevitable undesirable adverse reaction during orthodontic treatment …

Orthodontic force induces nerve injury-like transcriptomic changes driven by TRPV1-expressing afferents in mouse trigeminal ganglia

S Wang, MK Chung - Molecular Pain, 2020 - journals.sagepub.com
Orthodontic force produces mechanical irritation and localized inflammation in the
periodontium, which causes pain in most patients. Nocifensive behaviors resulting from …

Functional characterization of nociceptive mechanisms involved in fibromyalgia and electroacupuncture

B Lottering, YW Lin - Brain research, 2021 - Elsevier
The diagnosis and treatment of chronic pain in diseases such as fibromyalgia (FM) are
lacking effective standardised protocols that can be widely accessed and implemented by …