Metabolic diseases and their complications impose health and economic burdens
worldwide. Evidence from past experimental studies and clinical trials suggests our body …

Insulin resistance (IR) and the associated hyperinsulinemia are early pathophysiological
changes which, if not well treated, can lead to type 2 diabetes, endothelial dysfunction and …

Rising rates of insulin resistance and an ageing population are set to exact an increasing toll
on individuals and society. Here we examine the contribution of age and insulin resistance …

Sarcopenic obesity is characterized by concurrent obesity and muscle wasting (sarcopenia)
and is common in the elderly. Sarcopenic obesity has steadily increased as the aging …

Diabetes mellitus (DM) constitutes a chronic metabolic disease characterized by elevated
levels of blood glucose which can also lead to the so-called diabetic vascular complications …

Various evidences have unveiled the significance of Vitamin D in diverse processes which
include its action in prevention of immune dysfunction, cancer and cardiometabolic …

The global burden of type 2 diabetes (T2DM) has led to significant interest in finding novel
and effective therapeutic targets for this chronic disorder. Bioactive food components have …

In the frame of metabolic syndrome, type 2 diabetes emerges along a continuum of the risk
from the clustering of all its components, namely visceral obesity, high blood pressure and …

The transgender (trans) population includes individuals with gender identities more fittingly
aligned with the opposite sex or with an alternative that transcends the classical dipole of …

The sodium–glucose cotransporter 2 (SGLT2) mainly carries out glucose reabsorption in the
kidney. Familial renal glycosuria, which is a mutation of SGLT2, is known to excrete glucose …