[HTML][HTML] RGD-binding integrins revisited: how recently discovered functions and novel synthetic ligands (re-) shape an ever-evolving field
Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …
investigated as therapeutic targets over the last decades, motivated by their multiple …
[HTML][HTML] Platelet physiology
T Gremmel, AL Frelinger III… - Seminars in thrombosis …, 2016 - thieme-connect.com
Platelets are the smallest blood cells, numbering 150 to 350× 10 9/L in healthy individuals.
The ability of activated platelets to adhere to an injured vessel wall and form aggregates was …
The ability of activated platelets to adhere to an injured vessel wall and form aggregates was …
Core/shell nanoparticles in biomedical applications
Nanoparticles have several exciting applications in different areas and biomedial field is not
an exception of that because of their exciting performance in bioimaging, targeted drug and …
an exception of that because of their exciting performance in bioimaging, targeted drug and …
RGD-based strategies to target alpha (v) beta (3) integrin in cancer therapy and diagnosis
The integrin αvβ3 plays an important role in angiogenesis. It is expressed on tumoral
endothelial cells as well as on some tumor cells. RGD peptides are well-known to bind …
endothelial cells as well as on some tumor cells. RGD peptides are well-known to bind …
Imaging and drug delivery using theranostic nanoparticles
Nanoparticle technologies are significantly impacting the development of both therapeutic
and diagnostic agents. At the intersection between treatment and diagnosis, interest has …
and diagnostic agents. At the intersection between treatment and diagnosis, interest has …
[HTML][HTML] Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma
M Benezra, O Penate-Medina… - The Journal of …, 2011 - Am Soc Clin Investig
Nanoparticle-based materials, such as drug delivery vehicles and diagnostic probes,
currently under evaluation in oncology clinical trials are largely not tumor selective. To be …
currently under evaluation in oncology clinical trials are largely not tumor selective. To be …
Photoacoustic imaging in the second near-infrared window: a review
PK Upputuri, M Pramanik - Journal of biomedical optics, 2019 - spiedigitallibrary.org
Photoacoustic (PA) imaging is an emerging medical imaging modality that combines optical
excitation and ultrasound detection. Because ultrasound scatters much less than light in …
excitation and ultrasound detection. Because ultrasound scatters much less than light in …
Carbon nanotubes for biomedical imaging: the recent advances
This article reviews the latest progresses regarding the applications of carbon nanotubes
(CNTs), including single-walled carbon nanotubes (SWNTs) and multi-walled carbon …
(CNTs), including single-walled carbon nanotubes (SWNTs) and multi-walled carbon …
Molecular imaging of the tumor microenvironment
The tumor microenvironment plays a critical role in tumor initiation, progression, metastasis,
and resistance to therapy. It is different from normal tissue in the extracellular matrix …
and resistance to therapy. It is different from normal tissue in the extracellular matrix …
Copper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research
CJ Anderson, R Ferdani - Cancer Biotherapy and …, 2009 - liebertpub.com
Summation Copper-64 (T1/2= 12.7 hours; β+, 0.653 MeV [17.8%]; β−, 0.579 MeV [38.4%])
has decay characteristics that allow for positron emission tomography (PET) imaging and …
has decay characteristics that allow for positron emission tomography (PET) imaging and …