[HTML][HTML] RGD-binding integrins revisited: how recently discovered functions and novel synthetic ligands (re-) shape an ever-evolving field

BS Ludwig, H Kessler, S Kossatz, U Reuning - Cancers, 2021 - mdpi.com
Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

[HTML][HTML] Platelet physiology

T Gremmel, AL Frelinger III… - Seminars in thrombosis …, 2016 - thieme-connect.com
Platelets are the smallest blood cells, numbering 150 to 350× 10 9/L in healthy individuals.
The ability of activated platelets to adhere to an injured vessel wall and form aggregates was …

Core/shell nanoparticles in biomedical applications

K Chatterjee, S Sarkar, KJ Rao, S Paria - Advances in colloid and interface …, 2014 - Elsevier
Nanoparticles have several exciting applications in different areas and biomedial field is not
an exception of that because of their exciting performance in bioimaging, targeted drug and …

RGD-based strategies to target alpha (v) beta (3) integrin in cancer therapy and diagnosis

F Danhier, A Le Breton, V Préat - Molecular pharmaceutics, 2012 - ACS Publications
The integrin αvβ3 plays an important role in angiogenesis. It is expressed on tumoral
endothelial cells as well as on some tumor cells. RGD peptides are well-known to bind …

Imaging and drug delivery using theranostic nanoparticles

SM Janib, AS Moses, JA MacKay - Advanced drug delivery reviews, 2010 - Elsevier
Nanoparticle technologies are significantly impacting the development of both therapeutic
and diagnostic agents. At the intersection between treatment and diagnosis, interest has …

[HTML][HTML] Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma

M Benezra, O Penate-Medina… - The Journal of …, 2011 - Am Soc Clin Investig
Nanoparticle-based materials, such as drug delivery vehicles and diagnostic probes,
currently under evaluation in oncology clinical trials are largely not tumor selective. To be …

Photoacoustic imaging in the second near-infrared window: a review

PK Upputuri, M Pramanik - Journal of biomedical optics, 2019 - spiedigitallibrary.org
Photoacoustic (PA) imaging is an emerging medical imaging modality that combines optical
excitation and ultrasound detection. Because ultrasound scatters much less than light in …

Carbon nanotubes for biomedical imaging: the recent advances

H Gong, R Peng, Z Liu - Advanced drug delivery reviews, 2013 - Elsevier
This article reviews the latest progresses regarding the applications of carbon nanotubes
(CNTs), including single-walled carbon nanotubes (SWNTs) and multi-walled carbon …

Molecular imaging of the tumor microenvironment

Z Zhou, ZR Lu - Advanced Drug Delivery Reviews, 2017 - Elsevier
The tumor microenvironment plays a critical role in tumor initiation, progression, metastasis,
and resistance to therapy. It is different from normal tissue in the extracellular matrix …

Copper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research

CJ Anderson, R Ferdani - Cancer Biotherapy and …, 2009 - liebertpub.com
Summation Copper-64 (T1/2= 12.7 hours; β+, 0.653 MeV [17.8%]; β−, 0.579 MeV [38.4%])
has decay characteristics that allow for positron emission tomography (PET) imaging and …