Salivary metabolomics: from diagnostic biomarker discovery to investigating biological function

A Gardner, G Carpenter, PW So - Metabolites, 2020 - mdpi.com
Metabolomic profiling of biofluids, eg, urine, plasma, has generated vast and ever-
increasing amounts of knowledge over the last few decades. Paradoxically, metabolomic …

Biological biomarkers of oral cancer

A Radaic, P Kamarajan, A Cho, S Wang… - Periodontology …, 2023 - Wiley Online Library
The oral squamous cell carcinoma (OSCC) 5 year survival rate of 41% has marginally
improved in the last few years, with less than a 1% improvement per year from 2005 to 2017 …

Oral squamous cell carcinoma diagnosed from saliva metabolic profiling

X Song, X Yang, R Narayanan… - Proceedings of the …, 2020 - National Acad Sciences
Saliva is a noninvasive biofluid that can contain metabolite signatures of oral squamous cell
carcinoma (OSCC). Conductive polymer spray ionization mass spectrometry (CPSI-MS) is …

Salivary metabolomics for diagnosis and monitoring diseases: challenges and possibilities

E Hyvärinen, M Savolainen, JJW Mikkonen, AM Kullaa - Metabolites, 2021 - mdpi.com
Saliva is a useful biological fluid and a valuable source of biological information. Saliva
contains many of the same components that can be found in blood or serum, but the …

Metabolic landscape of oral squamous cell carcinoma

JG Vitório, FF Duarte-Andrade… - Metabolomics, 2020 - Springer
Background Head and neck cancers are the seventh most common type of cancer
worldwide, with almost half of the cases affecting the oral cavity. Oral squamous cell …

Saliva–a new opportunity for fluid biopsy

Z Huang, X Yang, Y Huang, Z Tang, Y Chen… - Clinical Chemistry and …, 2023 - degruyter.com
Saliva is a complex biological fluid with a variety of biomolecules, such as DNA, RNA,
proteins, metabolites and microbiota, which can be used for the screening and diagnosis of …

Saliva and oral diseases

E Martina, A Campanati, F Diotallevi… - Journal of clinical …, 2020 - mdpi.com
Saliva is a fascinating biological fluid which has all the features of a perfect diagnostic tool.
In fact, its collection is rapid, simple, and noninvasive. Thanks to several transport …

Oral microbiome research on oral lichen planus: Current findings and perspectives

W Jung, S Jang - Biology, 2022 - mdpi.com
Simple Summary Oral lichen planus is a disease of the oral mucosa, which frequently affects
women aged 40 years or older. Though the T cell-mediated immune response is involved in …

Salivary metabolomics for oral cancer detection: a narrative review

K Panneerselvam, S Ishikawa, R Krishnan, M Sugimoto - Metabolites, 2022 - mdpi.com
The development of low-or non-invasive screening tests for cancer is crucial for early
detection. Saliva is an ideal biofluid containing informative components for monitoring oral …

Identification of possible salivary metabolic biomarkers and altered metabolic pathways in South American patients diagnosed with oral squamous cell carcinoma

M de Sá Alves, N de Sá Rodrigues, CM Bandeira… - Metabolites, 2021 - mdpi.com
Oral squamous cell carcinoma (OSCC) represents 90% of oral malignant neoplasms. The
search for specific biomarkers for OSCC is a very active field of research contributing to …