Importance The sequential model emerged from the awareness that the persistence of
residual symptoms and the frequent occurrence of psychiatric comorbidity were both …

Major depressive disorder (MDD) is highly disabling and typically runs a recurrent course.
Knowledge about prevention of relapse and recurrence is crucial to the long-term welfare of …

Clinical depression is one of the most common and debilitating of the psychiatric disorders.
1 Lifetime prevalence has been estimated at 16.2% and rates of comorbidity and risk for …

Relapse and recurrence following response to acute-phase treatment for major depressive
disorder (MDD) are prevalent and costly. In a meta-analysis of 28 studies including 1,880 …

Recent studies suggest that cognitive and behavioral interventions have enduring effects
that reduce risk for subsequent symptom return following treatment termination. These …

In this review of the last 5 years' developments in research into depression we focus on
recent advances and current controversies. We cover epidemiology and basic science as …

This report reviews recent research on the psychosocial aspects of the functional
gastrointestinal disorders (FGIDs). A review and evaluation of existing literature was …

Background: The mood disorders are prevalent and problematic. We review randomized
controlled psychotherapy trials to find those that are empirically supported with respect to …

BackgroundAlthough cognitive behavioural therapy (CBT) is claimed to be effective in
schizophrenia, major depression and bipolar disorder, there have been negative findings in …

Background Major depression is probably best seen as a chronically recurrent disorder, with
patients experiencing another depressive episode after remission. Therefore, attention to …