[HTML][HTML] The interplay between autophagy and ferroptosis presents a novel conceptual therapeutic framework for neuroendocrine prostate cancer

Y Wang, N Wu, J Li, J Liang, D Zhou, Q Cao, X Li… - Pharmacological …, 2024 - Elsevier
In American men, the incidence of prostate cancer (PC) is the highest among all types of
cancer, making it the second leading cause of mortality associated with cancer. For …

Identification of Molecular Markers Associated with Prostate Cancer Subtypes: An Integrative Bioinformatics Approach

I Granata, P Barboro - Biomolecules, 2024 - mdpi.com
Prostate cancer (PCa) is characterised by androgen dependency. Unfortunately, under anti-
androgen treatment pressure, castration-resistant prostate cancer (CRPC) emerges …

Reproducible preclinical models of androgen receptor driven human prostate cancer bone metastasis

JJ Yin, A Daryanani, F Lu, AT Ku, JR Bright… - The …, 2024 - Wiley Online Library
Background Preclinical models recapitulating the metastatic phenotypes are essential for
developing the next‐generation therapies for metastatic prostate cancer (mPC). We aimed to …

Genomic Portraits: Reflections into a Tumor's Response to Therapy

SF Slovin - Clinical Cancer Research, 2023 - AACR
Well-annotated matched tissue specimens both before and after initiation of androgen
receptor signaling inhibitors (ARSI) have revealed activation of unique signaling pathways …

Genomic profiling and clinical utility of circulating tumor DNA in metastatic prostate cancer: SCRUM-Japan MONSTAR SCREEN project

M Shiota, N Matsubara, T Kato, M Eto, T Osawa, T Abe… - BJC Reports, 2024 - nature.com
Abstract Background Circulating tumor DNA (ctDNA) testing has emerged as a novel tool for
cancer precision medicine. This study investigated the genomic profiling and clinical utility of …