Oxidative stress is defined as an imbalance between production of free radicals and reactive
metabolites or [reactive oxygen species (ROS)] and their elimination by through protective …

Sarcopenia, an age-related decline in skeletal muscle mass and function, dramatically
affects the quality of life. Although there is a consensus that sarcopenia is a multifactorial …

The NFE2L2 gene encodes the transcription factor Nrf2 best known for regulating the
expression of antioxidant and detoxification genes. Gene knockout approaches have …

Cardiovascular diseases (CVDs) are the world's leading killers, accounting for 30% deaths.
According to the WHO report, CVDs kill 17.9 million people per year, and there will be 22.2 …

Sulforaphane (SFN), a potent nuclear factor erythroid 2-related factor 2 (Nrf2) activator, is
present in the species of the Brassicaceae, especially in broccoli sprouts. In this study, the …

The intestinal immune system is continuously exposed to massive amounts of nanoparticles
derived from food. Whether nanoparticles from plants we eat daily have a role in maintaining …

Extensive research within the last several decades has revealed that the major risk factors
for most chronic diseases are infections, obesity, alcohol, tobacco, radiation, environmental …

There is substantial and promising evidence on the health benefits of consuming broccoli
and other cruciferous vegetables. The most important compound in broccoli, glucoraphanin …

Type 2 diabetes mellitus (T2DM) is characterised by chronic low-grade inflammation,
recently referred to as 'metaflammation', a relevant factor contributing to the development of …

Neurodegenerative diseases (NDDs) and cardiovascular diseases (CVDs) are illnesses that
affect the nervous system and heart, all of which are vital to the human body. To maintain …