This review considers antiviral nucleoside analog (NA) drugs, including ribavirin, favipiravir,
and molnupiravir, which induce genome error catastrophe in SARS‐CoV or SARS‐CoV‐2 …

Chemical carcinogenesis involves a complex series of events, the earliest of which typically
include DNA damage and the fixation of DNA mutations. Sophisticated new techniques have …

The growth dynamics of bacterial pathogens within infected hosts are a fundamental but
poorly understood feature of most infections. We have focused on the in situ distribution and …

Objective: To evaluate the association of tenofovir disoproxil fumarate (TDF) use during
pregnancy with early growth parameters in HIV-exposed, uninfected (HEU) infants. Design …

The Surveillance Monitoring for ART Toxicities (SMARTT) cohort of the Pediatric HIV/AIDS
Cohort Study includes over 3,500 HIV-exposed but uninfected infants and children at 22 …

Nucleoside analogs were first approved by the US Food and Drug Administration for use
against HIV‐AIDS in 1987. Since then, these agents, now commonly referred to as …

Over the past three decades, perinatal HIV infection in the United States has evolved from a
fatal disease to a manageable chronic illness. As the majority of youth with perinatal HIV …

AIDS related mortality has fallen sharply in industrialised countries since 1996 following the
introduction of highly active antiretroviral therapy. This has been accompanied by an …

OBJECTIVE: Antiretroviral (ARV) drugs are routinely provided to HIV-infected pregnant
women to prevent HIV mother-to-child transmission. Although ARV use has significantly …

The provision of antiretroviral drugs for the prevention of mother-to-child HIV transmission
has been rising sharply in low-and middle-income countries. Changes to the World Health …