The significant role of amino acid metabolic reprogramming in cancer

X Liu, B Ren, J Ren, M Gu, L You, Y Zhao - Cell Communication and …, 2024 - Springer
Amino acid metabolism plays a pivotal role in tumor microenvironment, influencing various
aspects of cancer progression. The metabolic reprogramming of amino acids in tumor cells …

Empowering radiotherapy: Harnessing nanomedicines to enhance radiation response and boost antitumor efficacy

X Zhuo, R Aishajiang, Y Liang, P Du, P Lei, D Yu… - Coordination Chemistry …, 2024 - Elsevier
Radiotherapy (RT) is a conventional form of tumor treatment that uses X-ray irradiation to
eliminate tumors. Although RT plays an important role in treating tumor patients and …

Boosting Theranostic Performance of AIEgens Using Nanocatalyzer for Robust Cancer Immunotherapy

Y Li, Z Du, Y Zhang, X Kang, J Song… - Advanced Functional …, 2024 - Wiley Online Library
High‐performance theranostic systems are of paramount importance for achieving precise
image‐guided cancer immunotherapy. Here, a novel nanoplatform is presented that …

Applications of Biodegradable Polymers in the Encapsulation of Anticancer Metal Complexes

M Redrado, Z Xiao, K Upitak, BT Doan… - Advanced Functional …, 2024 - Wiley Online Library
Metal complexes have recently attracted a lot of attention, particularly as anticancer and
antibacterial agents, owing to their versatile mechanisms and easily tunable characteristics …

Engineering AIEgens-Tethered Gold Nanoparticles with Enzymatic Dual Self-Assembly for Amplified Cancer-Specific Phototheranostics

J Bian, Y Xu, M Sun, Z Ma, H Li, C Sun, F Xiong… - ACS …, 2024 - ACS Publications
Accurate imaging and precise treatment are critical to controlling the progression of
pancreatic cancer. However, current approaches for pancreatic cancer theranostics suffer …

Tumor Metabolism: A New Field for the Treatment of Glioma

X Chai, Y Zhang, W Zhang, K Feng, Y Jiang… - Bioconjugate …, 2024 - ACS Publications
The clinical treatment of glioma remains relatively immature. Commonly used clinical
treatments for gliomas are surgery combined with chemotherapy and radiotherapy, but there …

[HTML][HTML] Immune Checkpoint Inhibitors Rechallenge in Non-Small Cell Lung Cancer: Current Evidence and Future Directions

X Gang, J Yan, X Li, S Shi, L Xu, R Liu, L Cai, H Li… - Cancer Letters, 2024 - Elsevier
Immunotherapy, remarkably immune checkpoint inhibitors (ICIs), has significantly altered the
treatment landscape for non-small cell lung cancer (NSCLC). Despite their success, the …

A Bimetallic Nanomodulator to Reverse Immunosuppression via Sonodynamic‐Ferroptosis and Lactate Metabolism Modulation

X Deng, Y Zhu, Z Dai, Q Liu, Z Song, T Liu, Y Huang… - Small, 2024 - Wiley Online Library
Triple‐negative breast cancer (TNBC) responds poorly to immunotherapy due to insufficient
immunogenicity and highly immunosuppressive tumor microenvironment (TME). Herein, an …

Golgi apparatus-targeted BODIPY-based photosensitizer synergized with glutaminase inhibition for enhanced photodynamic therapy

J Li, Q Yu, Y Li, D Xu, S Yin - Dyes and Pigments, 2024 - Elsevier
Photodynamic therapy (PDT) is a precise and less toxic side effect treatment strategy.
However, the inherently short lifespan and constrained diffusion range of reactive oxygen …

Recent process of using nanoparticles in the T cell-based immunometabolic therapy

B Chen, Y Li, H Wang - Nanotechnology Reviews, 2024 - degruyter.com
Immunotherapy is currently the main treatment for malignant tumors by activating immune
cell. Metabolic reprogramming in tumor microenvironment can greatly affect the function of …