The aldo-keto reductase superfamily and its role in drug metabolism and detoxification
OA Barski, SM Tipparaju, A Bhatnagar - Drug metabolism reviews, 2008 - Taylor & Francis
The aldo-keto reductase (AKR) superfamily comprises enzymes that catalyze redox
transformations involved in biosynthesis, intermediary metabolism, and detoxification …
transformations involved in biosynthesis, intermediary metabolism, and detoxification …
Microbial cells as catalysts for stereoselective red–ox reactions
JD Carballeira, MA Quezada, P Hoyos, Y Simeó… - Biotechnology …, 2009 - Elsevier
Enzyme catalyzed reactions are commonly used at laboratory or industrial scale. Contrarily,
the whole cell catalyzed reactions are restricted to special cases. The tremendous advances …
the whole cell catalyzed reactions are restricted to special cases. The tremendous advances …
[HTML][HTML] Yeast biotechnology: teaching the old dog new tricks
Yeasts are regarded as the first microorganisms used by humans to process food and
alcoholic beverages. The technology developed out of these ancient processes has been …
alcoholic beverages. The technology developed out of these ancient processes has been …
[HTML][HTML] Yeast cell factories for fine chemical and API production
B Pscheidt, A Glieder - Microbial Cell Factories, 2008 - Springer
This review gives an overview of different yeast strains and enzyme classes involved in
yeast whole-cell biotransformations. A focus was put on the synthesis of compounds for fine …
yeast whole-cell biotransformations. A focus was put on the synthesis of compounds for fine …
New trends in the recycling of NAD (P) H for the design of sustainable asymmetric reductions catalyzed by dehydrogenases
A Berenguer-Murcia… - Current Organic …, 2010 - ingentaconnect.com
Dehydrogenases are amongst the most promising enzymes in biocatalysis, due to their
ability to perform asymmetric and regioselective reductions of both ketones and double …
ability to perform asymmetric and regioselective reductions of both ketones and double …
[HTML][HTML] Whole-cell bioreduction of aromatic α-keto esters using Candida tenuis xylose reductase and Candida boidinii formate dehydrogenase co-expressed in …
R Kratzer, M Pukl, S Egger, B Nidetzky - Microbial Cell Factories, 2008 - Springer
Background Whole cell-catalyzed biotransformation is a clear process option for the
production of chiral alcohols via enantioselective reduction of precursor ketones. A wide …
production of chiral alcohols via enantioselective reduction of precursor ketones. A wide …
The CCAAT box binding transcription factor, nuclear factor-Y (NF-Y) regulates transcription of human aldo-keto reductase 1C1 (AKR1C1) gene
R Pallai, H Simpkins, J Chen, HK Parekh - Gene, 2010 - Elsevier
Dihydrodiol dehydrogenases are a family of aldo-keto reductases (AKR1Cs) involved in the
metabolism of steroid hormones and xenobiotics. Herein, we have cloned and characterized …
metabolism of steroid hormones and xenobiotics. Herein, we have cloned and characterized …
Integration of newly isolated biocatalyst and resin-based in situ product removal technique for the asymmetric synthesis of (R)-methyl mandelate
JL Guo, XQ Mu, Y Xu - Bioprocess and biosystems engineering, 2010 - Springer
The enantioselective reduction of methyl benzoylformate to (R)-methyl mandelate, an
important pharmaceutical intermediate and a versatile resolving agent, was investigated in …
important pharmaceutical intermediate and a versatile resolving agent, was investigated in …
Candida tenuis xylose reductase catalysed reduction of acetophenones: the effect of ring-substituents on catalytic efficiency
M Vogl, R Kratzer, B Nidetzky, L Brecker - Organic & biomolecular …, 2011 - pubs.rsc.org
The catalytic efficiencies of Candida tenuisxylose reductase catalysed reductions of mono-
substituted acetophenones are in reasonable correlation with the σ-Hammett coefficients of …
substituted acetophenones are in reasonable correlation with the σ-Hammett coefficients of …
Systematic strain construction and process development: Xylitol production by Saccharomyces cerevisiae expressing Candida tenuis xylose reductase in wild-type or …
SM Pratter, T Eixelsberger, B Nidetzky - Bioresource technology, 2015 - Elsevier
A novel Saccharomyces cerevisiae whole-cell biocatalyst for xylitol production based on
Candida tenuis xylose reductase (CtXR) is presented. Six recombinant strains expressing …
Candida tenuis xylose reductase (CtXR) is presented. Six recombinant strains expressing …