Bone is a dynamic tissue constantly responding to environmental changes such as
nutritional and mechanical stress. Bone homeostasis in adult life is maintained through bone …

Chronic periapical periodontitis (CAP) is a typical oral disease in which periodontal
inflammation caused by an odontogenic infection eventually leads to bone loss …

An appropriate immune microenvironment, governed by macrophages, is essential for rapid
tissue regeneration after biomaterial implantation. The macrophage phenotypes, M1 …

Mesenchymal stem cell-based therapies are promising tools for bone tissue regeneration.
However, tracking cells and maintaining them in the site of injury is difficult. A potential …

Bacteria are one of the significant causes of infection in the body after scaffold implantation.
Effective use of nanotechnology to overcome this problem is an exciting and practical …

Although substantial data indicate that the osteogenic potential of periodontal ligament stem
cells (PDLSCs) is compromised under inflammatory conditions, the underlying mechanism …

Iron is one of the essential mineral elements for the human body and this nutrient deficiency
is a worldwide public health problem. Iron is essential in oxygen transport, participates in …

The gut microbiome is a collection of microorganisms and parasites in the gastrointestinal
tract. Many factors can affect this community's composition, such as age, sex, diet …

Osteoporosis is known as an imbalance in bone catabolism and anabolism. Overactive
bone resorption causes bone mass loss and increased incidence of fragility fractures …

A fundamental understanding of inflammation and tissue healing suggests that the precise
regulation of the inflammatory phase, both in terms of location and timing, is crucial for bone …