We have identified a third member of the junctional adhesion molecule (JAM) family. At the
protein level JAM3 displays 36 and 32% identity to JAM2 and JAM1, respectively. The …

In the clinical setting, drug concentrations in cerebrospinal fluid (CSF) are sometimes used
as a surrogate for drug concentrations at the target site within the brain. However, the brain …

Objectives To examine the association between blood-brain barrier (BBB) integrity, brain
volume and cognitive dysfunction in adult patients with systemic lupus erythematosus (SLE) …

Age-related blood-brain barrier (BBB) disruption and cerebromicrovascular rarefaction
contribute importantly to the pathogenesis of both vascular cognitive impairment and …

Cell replacement therapy may have the potential to promote brain repair and recovery after
stroke. To compare how focal cerebral ischemia affects the entry, migration, and phenotypic …

Much of the controversy over the causes of electro-hypersensitivity (EHS) and multiple
chemical sensitivity (MCS) lies in the absence of both recognized clinical criteria and …

Cognitive performances are tightly associated with the maximal aerobic exercise capacity,
both of which decline with age. The benefits on mental health of regular exercise, which …

The blood-brain barrier (BBB) efficiently restricts penetration of therapeutic agents to the
brain from the periphery. Therefore, discovery of new modalities allowing for effective …

Electromagnetic field (EMF) modalities offer an alternative to the increasing use of
pharmaceutical products for therapeutic use. This book presents state-of-the-art EMF use in …

The blood–brain barrier (BBB) is of pivotal importance to maintain homeostasis of the CNS,
as it closely regulates the composition of the interstitial fluid in the brain. Unfortunately …