Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: the role of Epstein–Barr virus and the gut–brain axis
K Hashimoto - Molecular Psychiatry, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public …
Sex and gender differences in intensive care medicine
H Merdji, MT Long, M Ostermann, M Herridge… - Intensive care …, 2023 - Springer
Despite significant advancements in critical care medicine, limited attention has been given
to sex and gender disparities in management and outcomes of patients admitted to the …
to sex and gender disparities in management and outcomes of patients admitted to the …
An update on management of adult patients with acute respiratory distress syndrome: an official American Thoracic Society clinical practice guideline
Background: This document updates previously published Clinical Practice Guidelines for
the management of patients with acute respiratory distress syndrome (ARDS), incorporating …
the management of patients with acute respiratory distress syndrome (ARDS), incorporating …
Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage
C Beck, D Ramanujam, P Vaccarello… - Nature …, 2023 - nature.com
Recent studies of severe acute inflammatory lung disease including COVID-19 identify
macrophages to drive pulmonary hyperinflammation and long-term damage such as fibrosis …
macrophages to drive pulmonary hyperinflammation and long-term damage such as fibrosis …
Endothelial cell‐derived extracellular vesicles expressing surface VCAM1 promote sepsis‐related acute lung injury by targeting and reprogramming monocytes
L Wang, Y Tang, J Tang, X Liu, S Zi, S Li… - Journal of …, 2024 - Wiley Online Library
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a common life‐
threatening syndrome with no effective pharmacotherapy. Sepsis‐related ARDS is the main …
threatening syndrome with no effective pharmacotherapy. Sepsis‐related ARDS is the main …
METTL3‐mediated N6‐methyladenosine exacerbates ferroptosis via m6A‐IGF2BP2‐dependent mitochondrial metabolic reprogramming in sepsis‐induced acute lung …
H Zhang, D Wu, Y Wang, K Guo… - Clinical and …, 2023 - Wiley Online Library
Neutrophil extracellular traps (NETs), released by polymorphonuclear neutrophils (PMNs),
exert a robust antimicrobial function in infectious diseases such as sepsis. NETs also …
exert a robust antimicrobial function in infectious diseases such as sepsis. NETs also …
Acute organ injury and long-term sequelae of severe pneumococcal infections
Streptococcus pneumoniae (Spn) is a major public health problem, as it is a main cause of
otitis media, community-acquired pneumonia, bacteremia, sepsis, and meningitis. Acute …
otitis media, community-acquired pneumonia, bacteremia, sepsis, and meningitis. Acute …
Overview of the potential use of fluvoxamine for COVID-19 and long COVID
K Hashimoto - Discover Mental Health, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) has presented a serious worldwide threat to
public health since its emergence in late 2019. From a safety point of view, drug repurposing …
public health since its emergence in late 2019. From a safety point of view, drug repurposing …
A diagnostic model for sepsis-induced acute lung injury using a consensus machine learning approach and its therapeutic implications
Y Zheng, J Wang, Z Ling, J Zhang, Y Zeng… - Journal of Translational …, 2023 - Springer
Background A significant proportion of septic patients with acute lung injury (ALI) are
recognized late due to the absence of an efficient diagnostic test, leading to the postponed …
recognized late due to the absence of an efficient diagnostic test, leading to the postponed …
Alpha-linolenic acid pretreatment alleviates NETs-induced alveolar macrophage pyroptosis by inhibiting pyrin inflammasome activation in a mouse model of sepsis …
C Liu, Y Zhou, Q Tu, L Yao, J Li, Z Yang - Frontiers in Immunology, 2023 - frontiersin.org
Background Neutrophil extracellular traps (NETs) can cause acute lung injury (ALI)/acute
respiratory distress syndrome (ARDS) by inducing macrophage pyroptosis. The purpose of …
respiratory distress syndrome (ARDS) by inducing macrophage pyroptosis. The purpose of …