A hospital-based study of the clinical characteristics of Clostridium difficile infection in children

JD Crews, HL Koo, ZD Jiang, JR Starke… - The Pediatric …, 2014 - journals.lww.com
Background: Clostridium difficile infection (CDI) is an increasingly important cause of
morbidity in hospitalized children. We describe the recent epidemiology of pediatric CDI at a …

Oral Vancomycin May Be Associated With Earlier Symptom Resolution Than Metronidazole for Hospitalized Children With Nonsevere Clostridioides difficile Infections

J Yin, LK Kociolek, RG Same, AJ Hsu… - Open forum …, 2019 - academic.oup.com
Objective National guidelines recommend oral vancomycin over oral metronidazole as first-
line treatment for nonsevere Clostridioides difficile infection (CDI) in adults. Guidelines …

Updated Management Guidelines for Clostridioides difficile in Paediatrics

M Gnocchi, M Gagliardi, P Gismondi, F Gaiani… - Pathogens, 2020 - mdpi.com
Clostridioides difficile, formerly known as Clostridium difficile, causes infections (CDI)
varying from self-limited diarrhoea to severe conditions, including toxic megacolon and …

Fecal microbiota transplantation in children: current concepts

B Gurram, PK Sue - Current opinion in pediatrics, 2019 - journals.lww.com
FMT is recognized as an effective treatment option for RCDI and is increasing sought by
parents. Although limited, pediatric studies to date on the use of FMT for RCDI demonstrate …

Epidemiology, outcomes, and predictors of mortality in hospitalized adults with Clostridium difficile infection

S Khanna, A Gupta, LM Baddour, DS Pardi - Internal and emergency …, 2016 - Springer
Studies have demonstrated an increasing Clostridium difficile infection (CDI) incidence in
hospitals and the community, with increasing morbidity and mortality. In this study, we …

Recurrent Clostridium difficile infection in children: patient risk factors and markers of intestinal inflammation

MR Nicholson, JD Crews, JR Starke… - The Pediatric …, 2017 - journals.lww.com
Background: The management of Clostridium difficile infection (CDI) in children is
complicated by recurrence rates of 20%–30%. The identification of risk factors associated …

Acid-Suppressing Agents and Risk for Clostridium difficile Infection in Pediatric Patients

KE Brown, CA Knoderer, KR Nichols… - Clinical …, 2015 - journals.sagepub.com
Background. Acid-suppressing agents have been associated with increased Clostridium
difficile infection (CDI) in adults. The objective of this study was to evaluate the association of …

Flooding and Clostridium difficile Infection: A Case-Crossover Analysis

CJ Lin, TJ Wade, ED Hilborn - International journal of environmental …, 2015 - mdpi.com
Clostridium difficile is a bacterium that can spread by water. It often causes acute
gastrointestinal illness in older adults who are hospitalized and/or receiving antibiotics; …

Risk factors for community-associated Clostridioides difficile infection in young children

MK Weng, SH Adkins, W Bamberg, MM Farley… - Epidemiology & …, 2019 - cambridge.org
The majority of paediatric Clostridioides difficile infections (CDI) are community-associated
(CA), but few data exist regarding associated risk factors. We conducted a case–control …

Clinical and Microbiological Characteristics of Clostridium difficile Infection Among Hospitalized Children in the Netherlands

SM van Dorp, E Smajlović, CW Knetsch… - Clinical Infectious …, 2017 - academic.oup.com
Background. Little is known about pediatric Clostridium difficile infection (CDI) epidemiology.
We describe the clinical and microbiological characteristics of CDI among hospitalized …