Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives

A Kumari, RK Singh - Bioorganic chemistry, 2019 - Elsevier
Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …

[HTML][HTML] The potential of pumpkin seeds as a functional food ingredient: A review

JM Dotto, JS Chacha - Scientific African, 2020 - Elsevier
Pumpkin seeds may be tiny, but they are densely packed with useful nutrients and
nutraceuticals such as amino acids, phytosterols, unsaturated fatty acids, phenolic …

Recent advances in metal‐catalyzed functionalization of indoles

K Urbina, D Tresp, K Sipps… - Advanced Synthesis & …, 2021 - Wiley Online Library
Indole is one of the most important heterocycles in organic synthesis, natural products, and
drug discovery. Recently, tremendous advances in the selective functionalization of indoles …

Inhalation Aromatherapy via Brain-Targeted Nasal Delivery: Natural Volatiles or Essential Oils on Mood Disorders

J Cui, M Li, Y Wei, H Li, X He, Q Yang, Z Li… - Frontiers in …, 2022 - frontiersin.org
Mood disorders, also often referred to as affective disorders, are a group of psychiatric
illnesses that severely impact mood and its related functions. The high medical expenditures …

Therapeutic role of alkaloids and alkaloid derivatives in cancer management

K Olofinsan, H Abrahamse, BP George - Molecules, 2023 - mdpi.com
Cancer is a neoplastic disease that remains a global challenge with a reported prevalence
that is increasing annually. Though existing drugs can be applied as single or combined …

Plant alkaloids: Structures and bioactive properties

EP Gutiérrez-Grijalva, LX López-Martínez… - Plant-derived bioactives …, 2020 - Springer
Alkaloids are nitrogen-containing natural products found in bacteria, fungi, animals, and
plants with complex and diverse structures. The widespread distribution of alkaloids along …

[HTML][HTML] Application of metabolic engineering to enhance the content of alkaloids in medicinal plants

S Mora-Vásquez, GG Wells-Abascal… - Metabolic Engineering …, 2022 - Elsevier
Plants are a rich source of bioactive compounds, many of which have been exploited for
cosmetic, nutritional, and medicinal purposes. Through the characterization of metabolic …

Inhibitory mechanisms of promising antimicrobials from plant byproducts: A review

M Qian, BB Ismail, Q He, X Zhang… - … Reviews in Food …, 2023 - Wiley Online Library
Plant byproducts and waste present enormous environmental challenges and an
opportunity for valorization and industrial application. Due to consumer demands for natural …

[HTML][HTML] Synthesis of indole derivatives as prevalent moieties present in selected alkaloids

MM Heravi, Z Amiri, K Kafshdarzadeh, V Zadsirjan - RSC advances, 2021 - pubs.rsc.org
Indoles are a significant heterocyclic system in natural products and drugs. They are
important types of molecules and natural products and play a main role in cell biology. The …

Transition‐Metal‐Catalyzed C−H Bond Functionalization of Arenes/Heteroarenes via Tandem C−H Activation and Subsequent Carbene Migratory Insertion Strategy

N Jha, NP Khot, M Kapur - The Chemical Record, 2021 - Wiley Online Library
The past decade has witnessed tremendous developments in transition‐metal‐catalyzed C−
H bond activation and subsequent carbene migratory insertion reactions, thus assisting in …