The goal of a biomaterial is to support the bone tissue regeneration process at the defect site
and eventually degrade in situ and get replaced with the newly generated bone tissue …

During the past two decades, tissue engineering and the regenerative medicine field have
invested in the regeneration and reconstruction of pathologically altered tissues, such as …

Alginate is a biopolymer extensively utilized in numerous applications. Hydrogel forming
property, chemical structure with hydroxyl and carboxylate moieties, biocompatibility …

Tissue engineering and regenerative medicine has been providing exciting technologies for
the development of functional substitutes aimed to repair and regenerate damaged tissues …

Bone substitutes are being increasingly used in surgery as over two millions bone grafting
procedures are performed worldwide per year. Autografts still represent the gold standard …

Alginate as a naturally-derived biomaterial with marine algae sources has gained much
attention in both laboratorial and industrial applications due to its structural and chemical …

As a natural linear polysaccharide, alginate can be gelled into calcium alginate fiber and
exploited for functional material applications. Owing to its high hygroscopicity …

The usage of plant origin natural gum polysaccharides in various biomedical applications is
steadily rising in recent years because of their peculiar properties like biocompatibility …

Recently, a wider spectrum of bio-based materials and materials-based novel constructs
and systems has been engineered with high interests. The key objective is to help for an …

Highlights•Electrospun scaffolds physically mimic the native extracellular matrix.•Techniques
for physicochemical and biological characterization of scaffolds are discussed.•MSCs have …