Background Inflammation in the lung is the body's natural response to injury. It acts to
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …

Wound repair is a complex biologic process which becomes abnormal in numerous disease
states. Although in vitro models have been important in identifying critical repair pathways in …

The term 'in silico clinical trials indicates the use of individualised computer simulation in the
development or regulatory evaluation of a medicinal product, medical device, or medical …

Effective translational methodologies for knowledge representation are needed in order to
make strides against the constellation of diseases that affect the world today. These …

Abstract Systems Biology has taken advantage of computational tools and high-throughput
experimental data to model several biological processes. These include signaling, gene …

We present a survey of recent advancements in the emerging field of patient-specific
modeling (PSM). Researchers in this field are currently simulating a wide variety of tissue …

OBJECTIVES/HYPOTHESES: The objective was to assess the utility of selected “resonant
voice”(RV) exercises for the reduction of acute vocal fold inflammation. The hypothesis was …

Single-cell 'omics methodology has yielded unprecedented insights based largely on data-
centric informatics for reducing, and thus interpreting, massive datasets. In parallel …

Inflammation is a normal, robust physiological process. It can also be viewed as a complex
system that senses and attempts to resolve homeostatic perturbations initiated from within …

A wide variety of modeling techniques have been applied towards understanding
inflammation. These models have broad potential applications, from optimizing clinical trials …