Research of the past 25 years has shown that astrocytes do more than participating and
building up the blood-brain barrier and detoxify the active synapse by reuptake of …

In the central nervous system (CNS) chondroitin sulfate proteoglycans, as one of the major
barrier-forming molecules, influence cell migration patterns and axon pathfinding. By …

The functional role of reactive astrocytes after stroke is controversial. To elucidate whether
reactive astrocytes contribute to neurological recovery, we compared behavioral outcome …

Glycosaminoglycans (GAGs) are essential polysaccharides in normal physiology and
disease. However, understanding of the contribution of specific GAG structures to specific …

Glycosaminoglycans (GAGs) play a crucial role in tissue homeostasis by regulating the
activity and diffusion of bioactive molecules. Incorporating GAGs into biomaterials has …

The concept of the tripartite synapse proposes that in addition to the presynapse and the
postsynaptic membrane closely apposed processes of astrocytes constitute an integral part …

Perineuronal nets (PNNs) are specialized extracellular matrix aggregates surrounding
distinct neuronal populations and regulating synaptic functions and plasticity. Previous …

Despite progress in use of decellularized lung scaffolds in ex vivo lung bioengineering
schemes, including use of gels and other materials derived from the scaffolds, the detailed …

The orderly development of the nervous system is characterized by phases of cell
proliferation and differentiation, neural migration, axonal outgrowth and synapse formation …

The adult spinal cord harbours a population of multipotent neural precursor cells (NPCs)
with the ability to replace oligodendrocytes. However, despite this capacity, proliferation and …