How do monomorphic bacteria evolve? The Mycobacterium tuberculosis complex and the awkward population genetics of extreme clonality

C Stritt, S Gagneux - Peer Community Journal, 2023 - peercommunityjournal.org
Exchange of genetic material through sexual reproduction or horizontal gene transfer is
ubiquitous in nature. Among the few outliers that rarely recombine and mainly evolve by de …

Advancing animal tuberculosis surveillance using culture-independent long-read whole-genome sequencing

G Ghielmetti, J Loubser, TJ Kerr, T Stuber… - Frontiers in …, 2023 - frontiersin.org
Animal tuberculosis is a significant infectious disease affecting both livestock and wildlife
populations worldwide. Effective disease surveillance and characterization of …

Genomic epidemiology sheds light on the emergence and spread of Mycobacterium bovis Eu2 Clonal Complex in Portugal

AC Pereira, AC Reis, MV Cunha - Emerging Microbes & Infections, 2023 - Taylor & Francis
Animal tuberculosis (TB) remains a serious concern for animal and human health.
Mycobacterium bovis circulates in multi-host systems, dominated by the European 2 clonal …

Deciphering the role of host species for two Mycobacterium bovis genotypes from the European 3 clonal complex circulation within a cattle‐badger‐wild boar …

L Canini, G Modenesi, A Courcoul… - …, 2023 - Wiley Online Library
Bovine tuberculosis is a common disease affecting cattle and wildlife worldwide.
Mycobacterium bovis circulation in wildlife decreases the efficacy of surveillance and control …

A critical evaluation of Mycobacterium bovis pangenomics, with reference to its utility in outbreak investigation

KM Ceres, MJ Stanhope, YT Gröhn - Microbial genomics, 2022 - microbiologyresearch.org
The increased accessibility of next generation sequencing has allowed enough genomes
from a given bacterial species to be sequenced to describe the distribution of genes in the …

Bovine tuberculosis in Central Ethiopian slaughterhouses and the identification of causative mycobacteria by multiplex real-time PCR

A Fromsa, AJK Conlan, S Srinivasan, M Zeleke… - BMC microbiology, 2024 - Springer
Background Bovine tuberculosis (bTB) is a chronic disease caused by members of the
Mycobacterium tuberculosis complex (MTBC) that ultimately leads to the development of …

Diversification of gene content in the Mycobacterium tuberculosis complex is determined by phylogenetic and ecological signatures

TT Silva-Pereira, NC Soler-Camargo… - Microbiology …, 2024 - Am Soc Microbiol
We analyzed the pan-genome and gene content modulation of the most diverse genome
data set of the Mycobacterium tuberculosis complex (MTBC) gathered to date. The closed …

Defining the genes required for survival of Mycobacterium bovis in the bovine host offers novel insights into the genetic basis of survival of pathogenic mycobacteria

AJ Gibson, J Stiens, IJ Passmore, V Faulkner… - Mbio, 2022 - Am Soc Microbiol
Tuberculosis has severe impacts on both humans and animals. Understanding the genetic
basis of survival of both Mycobacterium tuberculosis, the human-adapted species, and …

Mycobacterium bovis and M. caprae in Bulgaria: insight into transmission and phylogeography gained through whole-genome sequencing

V Valcheva, C Perea, T Savova-Lalkovska… - BMC Veterinary …, 2022 - Springer
Background This study aimed to characterize recent Mycobacterium bovis/M. caprae
isolates from Bulgaria by whole-genome sequencing (WGS) to gain a first insight into their …

[HTML][HTML] First time whole genome sequencing of Mycobacterium bovis from the environment supports transmission at the animal-environment interface

AC Pereira, D Pinto, MV Cunha - Journal of Hazardous Materials, 2024 - Elsevier
Spreading of Mycobacterium bovis causing animal tuberculosis (TB) at livestock-wildlife-
environment interfaces remains a significant problem. Recently, we provided evidence of …