[HTML][HTML] Sex-dependent factors of alcohol and neuroimmune mechanisms

B Cruz, V Borgonetti, M Bajo, M Roberto - Neurobiology of Stress, 2023 - Elsevier
Excessive alcohol use disrupts neuroimmune signaling across various cell types, including
neurons, microglia, and astrocytes. The present review focuses on recent, albeit limited …

Clinical and preclinical evidence for gut microbiome mechanisms in substance use disorder.

RS Hofford, DD Kiraly - Biological Psychiatry, 2023 - Elsevier
Substance use disorders are a set of recalcitrant neuropsychiatric conditions that cause
tremendous amounts of morbidity and mortality and are amongst the leading causes of loss …

Increased anxiolytic effect in aged female rats and increased motoric behavior in aged male rats to acute alcohol administration: Comparison to younger animals

DB Matthews, G Rossmann, SJ Matthews… - Pharmacology …, 2024 - Elsevier
The population of most countries in the world is increasing and understanding risk factors
that can influence the health of the older population is critical. Older adults consume alcohol …

On the critical need to investigate the effect of alcohol in the older population.

DB Matthews, GF Koob - Alcohol, 2023 - psycnet.apa.org
This article discusses the critical need to investigate the effect of alcohol in the older
population. Perhaps one of the most critical issues facing alcohol researchers is …

Impact of Elevated Brain IL-6 in Transgenic Mice on the Behavioral and Neurochemical Consequences of Chronic Alcohol Exposure

DL Gruol, D Calderon, S Huitron-Resendiz… - Cells, 2023 - mdpi.com
Alcohol consumption activates the neuroimmune system of the brain, a system in which
brain astrocytes and microglia play dominant roles. These glial cells normally produce low …

Major Psychiatric Disorders

W Walz - The Gliocentric Brain: Phenotype Plasticity of the …, 2024 - Springer
Glial and immune cells are involved to various degrees in initiation and progression of
mental diseases. However, one must judge each disease separately for glial involvement as …

Exploring Sex Differences in the Effects of Alcohol Use and Age on Value-Driven Attention

JT Battista - 2022 - search.proquest.com
Alcohol misuse and aging are each associated with deficits in attention. As such, hazardous
alcohol use may increase the presence of these deficits as individuals age. Studies have …

Chronic intermittent ethanol exposure during adolescence produces sex-and age-dependent changes in anxiety and cognition without changes in microglia reactivity …

DB Matthews, S Scaletty, S Trapp… - Frontiers in Behavioral …, 2023 - frontiersin.org
Binge-like ethanol exposure during adolescence has been shown to produce long lasting
effects in animal models including anxiety-like behavior that can last into young adulthood …