In recent years scientific and technological advancements have been made in the research
and development of rate-controlled oral drug delivery systems by overcoming physiological …

The purpose of writing this review on floating drug delivery systems (FDDS) was to compile
the recent literature with special focus on the principal mechanism of floatation to achieve …

Purpose. We report on the development of a novel controlled-release gastric retention
system, which consists of a matrix tablet, coated with a permeable membrane. When …

Oral ingestion is the most convenient and commonly used method of drug delivery. More
than 50% of drug delivery systems available in the market are oral drug delivery systems …

The challenge to develop efficient gastroretentive dosage forms began about 20 years ago,
following the discovery of Helicobacter pylori by Warren and Marshall. In order to …

Food-drug interactions can be associated with alterations in the pharmacokinetic and
pharmacodynamic profile of various drugs that may have clinical implications. The various …

Optimized floating (F) and non‐floating (NF) hydrophilic matrix capsules have been
characterized in vitro with regard to their buoyancy or non—buoyancy capabilities and their …

Peroral floating dosage forms have up to now been used and prescribed without having
achieved any determination of their real floating capabilities versus time. Using a novel in …

The purpose of this study was to evaluate the possible advantages of floating and high-
density dosage forms and their influence on pharmacokinetic parameters. Atenolol was …

The intragastric behaviour of a floating multiple-unit system was assayed in humans. The
floating units used in this study, composed of a calcium alginate core separated by an air …