Introduction Aggressive variants of papillary thyroid cancer (PTC) have been described with
increasing frequency. These variants include diffuse sclerosing variant, tall cell variant …

In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has
received enthusiastic investigation, and significant progress has been made toward …

Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of
the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is …

Papillary thyroid carcinomas are the most common thyroid cancers and constitute more than
70% of thyroid malignancies. The most common etiologic factor is radiation, but genetic …

Advances in medical sciences and evidence-based medicine have led to momentous
changes in classification and management of thyroid neoplasms. Much progress has been …

Context: Because very few studies have examined the correlation between BRAF mutations
and clinicopathological features of papillary thyroid carcinoma (PTC), we analyzed here a …

Papillary thyroid carcinomas (PTC) are the most common thyroid tumors that usually have a
good prognosis. Recurrence, metastases, and cancer death may occur in a few patients and …

Background: The current edition of the World Health Organization (WHO) classification of
endocrine tumors introduced grading for follicular cell-derived thyroid cancer. Tumors with …

Gene expression profiling shows that, by gene signature, the difference between BRAF-
positive and BRAF-negative PTC is so distinct that BRAF-positive cancer may be regarded …

The presence of calcification is the most significant ultrasonographic finding in evaluating
thyroid nodules. Calcifications are more frequently detected in papillary thyroid carcinoma …