Fish feed intake, feeding behavior, and the physiological response of apelin to fasting and refeeding

D Assan, Y Huang, UF Mustapha, MN Addah… - Frontiers in …, 2021 - frontiersin.org
Feed is one of the most important external signals in fish that stimulates its feeding behavior
and growth. The intake of feed is the main factor determining efficiency and cost, maximizing …

International Union of Basic and Clinical Pharmacology. LXXIV. Apelin receptor nomenclature, distribution, pharmacology, and function

SL Pitkin, JJ Maguire, TI Bonner, AP Davenport - Pharmacological reviews, 2010 - ASPET
A gene encoding a novel class a G-protein-coupled receptor was discovered in 1993 by
homology cloning and was called APJ. It was designated an “orphan” receptor until 1998 …

Apelin stimulates glucose uptake through the PI3K/Akt pathway and improves insulin resistance in 3T3-L1 adipocytes

S Zhu, F Sun, W Li, Y Cao, C Wang, Y Wang… - Molecular and cellular …, 2011 - Springer
Apelin, a cytokine mainly secreted by adipocytes, is closely related with insulin resistance.
The underlying molecular mechanisms of how apelin affects insulin resistance, however, are …

[HTML][HTML] Apelin-13 administration protects against LPS-induced acute lung injury by inhibiting NF-κB pathway and NLRP3 inflammasome activation

H Zhang, S Chen, M Zeng, D Lin, Y Wang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Acute lung injury (ALI) is induced by a variety of external and internal
factors and leads to acute progressive respiratory failure. Previous studies have shown that …

Effects of apelin on the cardiovascular system

A Folino, PG Montarolo, M Samaja, R Rastaldo - Heart failure reviews, 2015 - Springer
Apelin is an endogenous peptide acting on the APJ receptor. It consists of several isoforms
characterized by different numbers of amino acids. The number of amino acids in the active …

Modulation of the apelin/APJ system in heart failure and atherosclerosis in man

SL Pitkin, JJ Maguire, RE Kuc… - British journal of …, 2010 - Wiley Online Library
Background and purpose: The aim of this study was to determine whether the apelin/APJ
system is altered in human cardiovascular disease by investigating whether the expression …

Neuroprotection of apelin and its signaling pathway

B Cheng, J Chen, B Bai, Q Xin - Peptides, 2012 - Elsevier
Apelin was initially isolated from bovine stomach and is an endogenous neuropeptide. It is a
native ligand of the apelin receptor (APJ). Some research has found that apelin peptides …

Neuroprotective gain of Apelin/APJ system

JX Zhou, NN Shuai, B Wang, X Jin, X Kuang, SW Tian - Neuropeptides, 2021 - Elsevier
Apelin is an endogenous ligand of G protein-coupled receptor APJ. In recent years, many
studies have shown that the apelin/APJ system has neuroprotective properties, such as anti …

Apelin alleviates diabetes-associated endoplasmic reticulum stress in the pancreas of Akita mice

H Chen, C Zheng, X Zhang, J Li, J Li, L Zheng… - Peptides, 2011 - Elsevier
Apelin, a newly identified bioactive adipokine, has been found to play important roles in
multiple diseases, including diabetes, hypertension and cardiovascular diseases with …

Apelin is a novel islet peptide

C Ringström, MD Nitert, H Bennet, M Fex, P Valet… - Regulatory peptides, 2010 - Elsevier
Apelin, a recently discovered peptide with wide tissue distribution, regulates feeding
behavior, improves glucose utilization, and inhibits insulin secretion. We examined whether …