Pathogenesis of the novel coronavirus infection COVID-19 is the subject of active research
around the world. COVID-19 caused by the SARS-CoV-2 is a complex disease in which …

In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is
known to be a tissue regulating vascular tone, cell growth and the interaction between the …

Owing to the unique ability of antibodies that bind the membrane proximal region of the
extracellular domain to trigger conformational changes leading to affinity modulation and …

Human and wildlife are continually exposed to a wide range of compounds and substances,
which reach the body through the air, water, food, or personal care products. Plasticizers are …

This report provides a review of early and late effects of radiation in normal tissues and
organs with respect to radiation protection. It was instigated following a recommendation in …

Rationale: The function of Nox4, a source of vascular H2O2, is unknown. Other Nox proteins
were identified as mediators of endothelial dysfunction. Objective: We determined the …

Evidence has been gathered regarding the association between angiogenesis and
inflammation in pathological situations. These two phenomena have long been coupled …

Rationale: Vascular endothelial growth factor (VEGF) is the main driver of angiogenesis and
vascular permeability via VEGF receptor 2 (VEGFR2), whereas lymphangiogenesis signals …

Microvesicles (MVs) which include microparticles (MPs) and exosomes are found in blood
circulation in normal physiologic conditions and are increased in a variety of diseases. This …

Nrf2 is a key transcription factor responsible for antioxidant defense in many tissues and
cells, including alveolar epithelium, endothelium, and macrophages. Furthermore, Nrf2 …