[HTML][HTML] The landscape of implantation and placentation: deciphering the function of dynamic RNA methylation at the maternal-fetal interface

S Wu, H Xie, Y Su, X Jia, Y Mi, Y Jia… - Frontiers in …, 2023 - frontiersin.org
The maternal-fetal interface is defined as the interface between maternal tissue and sections
of the fetus in close contact. RNA methylation modifications are the most frequent kind of …

Non-coding RNA regulates the immune microenvironment in recurrent spontaneous abortion (RSA): new insights into immune mechanisms

C Tang, W Hu - Biology of Reproduction, 2024 - academic.oup.com
Recurrent spontaneous abortion (RSA) has various causes, including chromosomal
abnormalities, prethrombotic state, and abnormal uterine anatomical factors. However, the …

Parental exposure to environmentally relevant concentrations of bisphenol-A bis (diphenyl phosphate) impairs vascular development in offspring through DNA/RNA …

C Wang, J Xu, S Luo, J Huang, D Ji, X Qiu… - Environmental …, 2023 - ACS Publications
Bisphenol-A bis (diphenyl phosphate)(BDP) has been increasingly detected in indoor
environmental and human samples. Little is known about its developmental toxicity …

[HTML][HTML] Identification and verification of diagnostic biomarkers in recurrent pregnancy loss via machine learning algorithm and WGCNA

C Wei, Y Wei, J Cheng, X Tan, Z Zhou, S Lin… - Frontiers in …, 2023 - frontiersin.org
Background Recurrent pregnancy loss defined as the occurrence of two or more pregnancy
losses before 20-24 weeks of gestation, is a prevalent and significant pathological condition …

[HTML][HTML] The role of RNA methylation in tumor immunity and its potential in immunotherapy

Y Li, H Jin, Q Li, L Shi, Y Mao, L Zhao - Molecular Cancer, 2024 - Springer
RNA methylation, a prevalent post-transcriptional modification, has garnered considerable
attention in research circles. It exerts regulatory control over diverse biological functions by …

[HTML][HTML] Immunologic insights in recurrent spontaneous abortion: Molecular mechanisms and therapeutic interventions

D Guan, W Sun, M Gao, Z Chen, X Ma - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Recurrent spontaneous abortion refers to the occurrence of two or more spontaneous
abortions before or during the early stages of pregnancy. The immune system plays a crucial …

[HTML][HTML] The role of N6-methyladenosine in macrophage polarization: A novel treatment strategy for non-alcoholic steatohepatitis

J Wu, J Pan, W Zhou, G Ji, Y Dang - Biomedicine & Pharmacotherapy, 2024 - Elsevier
RNA methylation modifications, as a widespread type of modification in eukaryotic cells,
especially N6-methyladenosine (m 6 A), are associated with many activities in organisms …

FTO protein regulates the TGF‐β signalling pathway through RNA N6‐methyladenosine modification to induce unexplained recurrent spontaneous abortion

J Zhang, X Liu, Y Gao - The FEBS Journal, 2024 - Wiley Online Library
Recent studies have revealed the involvement of RNA m6A modification in embryonic
development; however, the relationship between aberrant RNA m6A modification and …

[PDF][PDF] RNA 甲基化对小鼠早期胚胎发育过程的影响

汪璐, 颜景斌 - 生命科学, 2023 - lifescience.sinh.ac.cn
近年来, 研究发现RNA 修饰可调控不同的生理过程, 特别是在早期胚胎发育过程中起重要的作用.
RNA 的甲基化是哺乳动物细胞中存在的最普遍的RNA 修饰之一, 也是一种重要的RNA …

[HTML][HTML] ALKBH5 在不同免疫环境中的调控作用

张晓娴, 谢锦, 费欢, 邱郑 - Bioprocess, 2023 - hanspub.org
m6A 修饰在转录后水平调控多种细胞过程, 而RNA m6A 水平受RNA 去甲基化酶ALKBH5 调节,
维持正常的生理功能的同时也促进多种人类疾病发生发展. 在这篇综述中, 我们讨论了ALKBH5 …