The chemistry, geometry, topography and mechanical properties of biomaterials modulate
biochemical signals (in particular ligand-receptor binding events) that control cells-matrix …

Materials science offers a powerful tool to control mesenchymal stem cell (MSC) growth and
differentiation into functional phenotypes. A complex interplay between the extracellular …

Micropatterns of arginine–glycine–aspartic acid (RGD) on poly (ethylene glycol)(PEG)
hydrogels were fabricated. Under an appropriate size of microislands on this strong and …

Cell response to matrix rigidity has been explained by the mechanical properties of the actin-
talin-integrin-fibronectin clutch. Here the molecular clutch model is extended to account for …

Mesenchymal stem cells, characterized by their ability to differentiate into skeletal tissues
and self-renew, hold great promise for both regenerative medicine and novel therapeutic …

Growth factors (GFs) are powerful signaling molecules with the potential to drive
regenerative strategies, including bone repair and vascularization. However, GFs are …

The extracellular matrix (ECM) is a heterogeneous, connective network composed of fibrous
glycoproteins that coordinate in vivo to provide the physical scaffolding, mechanical stability …

The use of cellulose materials for biomedical applications is attractive due to their low cost,
biocompatibility, and biodegradability. Specific processing of cellulose to yield nanofibrils …

Appropriate mechanical properties and fast endothelialization of synthetic grafts are key to
ensure long-term functionality of implants. We used a newly developed biostable …

Controlling the adhesion of mammalian and bacterial cells at the interfaces between
synthetic materials and biological environments is a real challenge in the biomedical fields …