Highlights•AMR is a leading and constantly growing threat to global health.•The human
microbiome is an important AMR reservoir.•Human–animal–environment interactions favor …

Antibiotic resistance genes predate the therapeutic uses of antibiotics. However, the current
antimicrobial resistance crisis stems from our extensive use of antibiotics and the generation …

Municipal wastewater provides a representative sample of human fecal waste across a
catchment area and contains a wide diversity of microbes. Sequencing wastewater samples …

Domestic wastewater is a significant reservoir of antibiotic resistance genes, which pose
environmental and public health risks. We aimed to define an antibiotic resistome signature …

ABSTRACT In North America, beef production relies on the administration of antimicrobials
to manage disease. Bovine respiratory disease (BRD) is the most significant disease of beef …

Background Recent endeavours in metagenomics, exemplified by projects such as the
human microbiome project and TARA Oceans, have illuminated the complexities of …

Wastewater is considered a reservoir of antimicrobial resistance genes (ARGs), where the
abundant antimicrobial-resistant bacteria and mobile genetic elements facilitate horizontal …

Wastewater treatment plants are well-known point sources of emissions of antibacterial
resistance genes (ARGs) into the environment. Although most work to date has focused on …

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Activated sludge is the centerpiece of biological wastewater treatment, as it facilitates
removal of sewage-associated pollutants, fecal bacteria, and pathogens from wastewater …