Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …

Off-target effects of systemically administered drugs have been a major hurdle in designing
therapies with desired efficacy and acceptable toxicity. Developing targeting strategies to …

Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …

Cancer remains one of the world's leading causes of death. However, most conventional
chemotherapeutic drugs only show a narrow therapeutic window in patients because of their …

Chemotherapy, a major strategy for cancer treatment, lacks the specificity to localize the
cancer therapeutics in the tumor site, thereby affecting normal healthy tissues and …

Fluorouracil (5-FU) has become one of the most widely employed antimetabolite
chemotherapeutic agents in recent decades. It is considered a first line antineoplastic agent …

For drug delivery in cancer therapy, various stimuli-responsive hydrogel-based micro-
devices have been studied with great interest. Here, we present a new concept for a hybrid …

Because of the particular characteristics of the tumor microenvironment and tumor
angiogenesis, it is possible to design drug delivery systems that specifically target anti …

Poly (lactic-co-glycolic acid)(PLGA) is one of the most effective biodegradable polymeric
nanoparticles (NPs). It has been approved by the US FDA to use in drug delivery systems …